Browsing by Subject "mitochondrial disease"
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Frequency of duplications in the D-loop in patients with mitochondrial DNA deletions
(Elsevier B.V., 2002-10-09)Small duplications (miniduplications) of the D-loop of human mitochondrial DNA (mtDNA) have been described in patients with mtDNA deletions, mtDNA point mutations and in normal aged tissues. the origin of these miniduplications ...
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Nitric Oxide in Skeletal Muscle: Role on Mitochondrial Biogenesis and Function
(Mdpi Ag, 2012-12-01)Nitric oxide (NO) has been implicated in several cellular processes as a signaling molecule and also as a source of reactive nitrogen species (RNS). NO is produced by three isoenzymes called nitric oxide synthases (NOS), ...
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Nitric Oxide Synthesis Is Increased in Cybrid Cells with m.3243A > G Mutation
(Mdpi Ag, 2013-01-01)Nitric oxide (NO) is a free radical and a signaling molecule in several pathways, produced by nitric oxide synthase (NOS) from the conversion of L-arginine to citrulline. Supplementation of L-arginine has been used to treat ...