Now showing items 1-10 of 11

    • Bidirectional ventricular tachycardia with alternating right and left bundle branch block morphology in a patient with metastatic cardiac tumors 

      Dorfman, F. K.; Mesas, C. E.; Cirenza, C.; De Paola, AAV (Blackwell Publishing, 2006-07-01)
      A case is reported of bidirectional ventricular tachycardia and syncope in a 16-year-old male with a previous history of a paratesticular rhabdomyosarcoma that achieved complete remission with treatment. At the ...

    • Carcinoma espinocelular do lábio: avaliação de fatores prognósticos 

      Abreu, Marilda A. M. M. [UNIFESP]; Pimentel, Dalva Regina Neto [UNIFESP]; Silva, Olga M. P. [UNIFESP]; Blachman, Isaac T. [UNIFESP]; Michalany, Nilceo S. [UNIFESP]; Hirata, Cleonice Hitomi Watashi [UNIFESP]; Weckx, Luc Louis Maurice [UNIFESP]; Alchorne, Maurício Mota de Avelar [UNIFESP] (ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2004-12-01)
      Among lip cancers, 90% to 95% of them affect the lower lip and squamous cell carcinoma is the most frequent type. The TNM classification synthesizes the clinical characteristics of the tumor that allows prognosis and makes ...

    • Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells 

      Rodrigues, Mariana F.; Obre, Emilie; de Melo, Fabiana H. M. [UNIFESP]; Santos, Gilson C., Jr.; Galina, Antonio; Jasiulionis, Miriam G. [UNIFESP]; Rossignol, Rodrigue; Rumjanek, Franklin D.; Amoedo, Nivea D. (Portland Press Ltd, 2016)
      Tumours display different cell populations with distinct metabolic phenotypes. Thus, subpopulations can adjust to different environments, particularly with regard to oxygen and nutrient availability. Our results indicate ...

    • Evaluation of MCT1, MCT4 and CD147 Genes in Peripheral Blood Cells of Breast Cancer Patients and Their Potential Use as Diagnostic and Prognostic Markers 

      Luz, Maria Claudia de B.; Perez, Matheus M.; Azzalis, Ligia A. [UNIFESP]; Sousa, Luiz Vinicius de A.; Adami, Fernando; Fonseca, Fernando L. A. [UNIFESP]; Alves, Beatriz da C. A. (Mdpi Ag, 2017)
      Background: Patients with breast cancer-the deadliest cancer among women-are at constant risk of developing metastasis. Oxidative stress and hypoxia are common feature of tumor cells that can proliferate even in a resultant ...

    • Functional differences between two morphologically distinct cell subpopulations within a human colorectal carcinoma cell line 

      Solimene, A.c.c. [UNIFESP]; Carneiro, Celia Regina Whitaker [UNIFESP]; Melati, I. [UNIFESP]; Lopes, Jose Daniel [UNIFESP] (Associação Brasileira de Divulgação Científica, 2001-05-01)
      The LISP-I human colorectal adenocarcinoma cell line was isolated from a hepatic metastasis at the Ludwig Institute, São Paulo, SP, Brazil. The objective of the present study was to isolate morphologically different ...

    • Gliomas múltiplos: casos ilustrativos de quatro formas de apresentação 

      Franco, Clélia Maria Ribeiro [UNIFESP]; Malheiros, Suzana Maria Fleury [UNIFESP]; Nogueira, Roberto Gomes [UNIFESP]; Batista, Marcus Azzar Sabry [UNIFESP]; Santos, Adrialdo José [UNIFESP]; Abdala, Nitamar [UNIFESP]; Stávale, João Norberto [UNIFESP]; Ferraz, Fernando Antônio Patriani [UNIFESP]; Gabbai, Alberto Alain [UNIFESP] (Academia Brasileira de Neurologia - ABNEURO, 2000-03-01)
      Multiple gliomas are uncommon and may be classified according to: a) the time of presentation in early (at diagnosis) or late (during treatment); b) the characteristics of computed tomography or magnetic resonance imaging ...

    • Heparanase expression in circulating lymphocytes of breast cancer patients depends on the presence of the primary tumor and/or systemic metastasis 

      Theodoro, Therese Rachell; Matos, Leandro Luongo de [UNIFESP]; Sant'Anna, Aleksandra Vanessa Lambiasi; Fonseca, Fernando Luiz Affonso [UNIFESP]; Semedo, Patricia [UNIFESP]; Martins, Lourdes Conceicao; Nader, Helena Bonciani [UNIFESP]; Del Giglio, Auro; Pinhal, Maria Aparecida da Silva [UNIFESP] (Neoplasia Press, 2007-06-01)
      Heparanase is an endo-beta-glucuronidase that is capable of degrading heparan sulfate chains of proteoglycans, generating a variety of bioactive molecules such as growth factors and chemotactic and angiogenic agents. the ...

    • Mecanismo de ação do composto paladaciclo ferroceno 1:2 em modelos celulares de resistência e metástase tumoral 

      Bechara, Alexandre [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-06-30)
      Cancer therapy is one of the major challenges for medicine since 20th century, when the mechanisms of tumor cell biology in cancer development began to be better understood. Although some pharmacological therapeutic ...

    • Melanoma heterogeneity: differential, invasive, metastatic properties and profiles of cathepsin B, D and L activities in subclones of the B16F10-NEX22 cell line 

      Freitas, ZFO; Rodrigues, E. G.; Oliveira, V; Carmona, A. K.; Travassos, L. R. (Lippincott Williams & Wilkins, 2004-10-01)
      Tumour cell lines and in vivo growing tumours are heterogeneous, comprising different cell clones. To understand why some cells primarily invade a tissue, while others are more apt to metastasize, several clones from the ...

    • MicroRNAs in cancer treatment and prognosis 

      Schoof, Claudia Regina Gasque [UNIFESP]; Botelho, Eder Leite da Silva [UNIFESP]; Izzotti, Alberto; Vasques, Luciana dos Reis [UNIFESP] (E-century Publishing Corp, 2012-01-01)
      Disturbances in microRNA expression by epigenetic alterations and mutations may promote not only tumorigenesis but also tumor aggressiveness, invasion, metastasis, and resistance to chemotherapy and radiotherapy. Several ...