Now showing items 1-10 of 75

    • Acute cognitive effects of donepezil in young, healthy volunteers 

      Zaninotto, Ana L. C. [UNIFESP]; Bueno, Orlando F. A. [UNIFESP]; Pradella-Hallinan, Marcia [UNIFESP]; Tufik, Sergio [UNIFESP]; Rusted, Jenny; Stough, Con; Pompeia, Sabine [UNIFESP] (Wiley-Blackwell, 2009-08-01)
      Objective the acute nootropic potential of donepezil in young healthy volunteers has not been adequately investigated mainly because in previous studies: (1) effects were assessed before peak-plasma concentration (Tmax) ...

    • Acute glucocorticoid effects on the multicomponent model of working memory 

      Vaz, Leonardo Jose [UNIFESP]; Pradella-Hallinan, Marcia [UNIFESP]; Amodeo Bueno, Orlando Francisco [UNIFESP]; Pompeia, Sabine [UNIFESP] (Wiley-Blackwell, 2011-10-01)
      Objective in comparison with basal physiological levels, acute, high levels of cortisol affect learning and memory. Despite reports of cortisol-induced episodic memory effects, no study has used a comprehensive battery of ...

    • Amphetamine-induced memory impairment in a discriminative avoidance task is state-dependent in mice 

      Sanday, Leandro [UNIFESP]; Patti, Camilla de Lima [UNIFESP]; Zanin, Karina Agustini [UNIFESP]; Tufik, Sergio [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Cambridge Univ Press, 2013-04-01)
      In both humans and laboratory animals, the reports of cognitive effects following acute amphetamine (Amph) administration are mixed and depend, for example, on the timing of administration (e. g. before or after task ...

    • Análise da influência do sono na expressão da proteína quinase M zeta e na memória de ratos 

      Barros, Luísa Mendes Amando de [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2015-01-09)
      Memory comprises acquisition, consolidation and retrieval of information. After consolidation memories must be maintained, a process that seems to be mediated by an atypical isoform of protein kinase C (PKC), the protein ...

    • Anterograde effects of a single electroconvulsive shock on inhibitory avoidance and on cued fear conditioning 

      Oliveira, Maria Gabriela Menezes de [UNIFESP]; Bueno, Orlando Francisco Amodeo [UNIFESP]; Gugliano, Eric Boragan [UNIFESP] (Associação Brasileira de Divulgação Científica, 1998-08-01)
      A single electroconvulsive shock (ECS) or a sham ECS was administered to male 3-4-month-old Wistar rats 1, 2, and 4 h before training in an inhibitory avoidance test and in cued classical fear conditioning (measured by ...

    • Apathy Is not Associated with Performance in Brief Executive Tests in Patients with Mild Cognitive Impairment and Mild Alzheimer's Disease 

      Guimaraes, Henrique Cerqueira [UNIFESP]; Fialho, Patricia Paes; Carvalho, Viviane Amaral; Machado, Thais Helena; Santos, Etelvina Lucas; Caramelli, Paulo (Bentham Science Publ Ltd, 2014-01-01)
      Neuropsychological correlates of apathy in Alzheimer's disease (AD) may shed some light on the neurobiology of this behavioral disorder. Whereas previous research has suggested an association between apathy and executive ...

    • Auditory Processing in Children with Migraine: A Controlled Study 

      Agessi, Larissa Mendonca [UNIFESP]; Villa, Thais Rodrigues [UNIFESP]; Carvalho, Deusvenir de Souza [UNIFESP]; Pereira, Liliane Desgualdo [UNIFESP] (Georg Thieme Verlag Kg, 2017)
      Background This study aimed to investigate central auditory processing performance in children with migraine and compared with controls without headache. Methods Twenty-eight children of both sexes, aged between 8 and 12 ...

    • Behavioral changes resulting from the administration of cycloheximide in the pilocarpine model of epilepsy 

      Santos, J. G. dos; Longo, B. M.; Blanco, M. M.; Oliveira, MGM de; Mello, LEN (Elsevier B.V., 2005-12-20)
      Cycloheximide influences synaptic reorganization resulting from pilocarpine-induced status epilepticus (SE). To investigate the possible behavioral consequences of this effect, we subjected animals to pilocarpine-induced ...

    • Behavioural and neurochemical effects of phosphatidylserine in MPTP lesion of the substantia nigra of rats 

      Perry, J. C.; Da Cunha, C.; Anselmo-Franci, J.; Andreatini, R.; Miyoshi, E.; Tufik, Sergio [UNIFESP]; Vital, MABF (Elsevier B.V., 2004-01-26)
      The present study investigated the effects of intranigral MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) infusion on rats treated with phosphatidylserine and evaluated in two memory tasks and on striatal dopamine ...

    • Bovine brain phosphatidylserine attenuates scopolamine induced amnesia in mice 

      Claro, Flavia T. [UNIFESP]; Patti, Camilla L. [UNIFESP]; Abilio, Vanessa C. [UNIFESP]; Frussa-Filho, Roberto [UNIFESP]; Silva, Regina H. [UNIFESP] (Elsevier B.V., 2006-07-01)
      This study verifies the effects of bovine brain phosphatidylserine (PS) on passive avoidance (PA) and contextual fear conditioning (CFC) tests in scopolamine-treated mice. Mice received daily i.p. 50 mg/kg PS or 0.2 M Tris ...