Now showing items 1-10 of 17

    • Analgesic activity of a triterpene isolated from Scoparia dulcis L. (vassourinha) 

      Freire, Sonia Maria de Farias; Torres, Luce Maria Brandão [UNIFESP]; Roque, Nidia Franca; Souccar, Caden [UNIFESP]; Lapa, Antonio José [UNIFESP] (Instituto Oswaldo Cruz, Ministério da Saúde, 1991-01-01)
      Analgesic and anti-inflammatory activities of water (WE) and ethanolic (EE) extracts of Scoparia dulcis L. were investigated in rats and mice, and compared to the effects induced by Glutinol, a triterpene isolated by ...

    • Analgesic and antiinflammatory activities of the aqueous extract of Plantago major L. 

      Guillen Nunez, Maria Elena [UNIFESP]; Emim, Jose Artur da Silva [UNIFESP]; Souccar, Caden [UNIFESP]; Lapa, Antonio José [UNIFESP] (Swets Zeitlinger Publishers, 1997-04-01)
      This study aimed to validate the pharmacological effects of Plantago major L., a medicinal plant used to decrease pain and inflammation. The aqueous extract (AE) was prepared from the dried ground leaves. Pretreatment with ...

    • Antidepressant-like effect of Cecropia glazioui Sneth and its constituents - in vivo and in vitro characterization of the underlying mechanism 

      Rocha, F. F.; Lima-Landman, M. T. R.; Souccar, C.; Tanae, M. M.; De Lima, T. C. M.; Lapa, A. J. (Elsevier B.V., 2007-06-01)
      The present study aimed to characterize the antidepressant-like effect of a standardized aqueous extract (AE) of Cecropia glazioui Sneth and its purified fractions on in vivo (forced swimming test), ex vivo (hippocampal ...

    • Effect of Potato virus X on total phenol and alkaloid contents in Datura stramonium leaves 

      Duarte, Lígia Maria Lembo; Salatino, Maria Luiza Faria; Salatino, Antonio; Negri, Giuseppina [UNIFESP]; Barradas, Maria Mércia (Grupo Paulista de Fitopatologia, 2008-02-01)
      The present paper reports results of the effect of Potato virus X (PVX) on the contents of total phenols and alkaloids in leaves of Datura stramonium. A significant decrease in the contents of phenols and alkaloids was ...

    • Evaluation of the antiurolithiatic activity of the extract of Costus spiralis Roscoe in rats 

      Viel, Tãnia Araujo [UNIFESP]; Domingos, Cristina Diogo [UNIFESP]; Monteiro, Ana Paula da Silva [UNIFESP]; Lima-Landman, Maria Teresa Riggio [UNIFESP]; Lapa, Antônio José [UNIFESP]; Souccar, Caden [UNIFESP] (Elsevier B.V., 1999-08-01)
      The antiurolithiatic activity of the water extract of Costus spiralis Roscoe was tested on formation of calculi on implants of calcium oxalate crystals or zinc disc in the urinary bladder of rats. The plant is a species ...

    • Evaluation of the anxiolytic-like effects of Cecropia glazioui Sneth in mice 

      Rocha, F. F.; Lapa, A. J.; De Lima, TCM (Elsevier B.V., 2002-01-01)
      Cecropia glazioui Sneth has been used in most Latin American countries as an antihypertensive, cardiotonic, and antiasthmatic folk medicine. in the cardiovascular studies to define its antihypertensive action it was ...

    • Implementation of the Three Rs in the Human Hazard Assessment of Brazilian Medicinal Plants: An Evaluation of the Cytotoxic and Genotoxic Potentials of Dipteryx alata Vogel 

      Esteves-Pedro, Natalia M.; Rodas, Andrea C. D.; Dal Belo, Chariston A.; Oshima-Franco, Yoko; Santos, Marcio G. dos; Lopes, Patricia Santos [UNIFESP] (Frame, 2011-05-01)
      In Brazil, medicinal plants are widely used by the indigenous people, which leads to a constant requirement for toxicity tests to be performed on the plant extracts. Although the current Brazilian Directive 90/2004 on the ...

    • In vivo inhibition of gastric acid secretion by the aqueous extract of Scoparia dulcis L. in rodents 

      Mesia-Vela, Sonia; Bielavsky, Monica; Brandao Torres, Luce Maria; Freire, Sonia Maria; Lima-Landman, Maria Teresa R.; Souccar, Caden; Lapa, Antonio Jose (Elsevier B.V., 2007-05-04)
      The freeze-dried aqueous extract (AE) from the aerial parts of Scoparia dulcis was tested for its effects on experimental gastric hypersecretion and ulcer in rodents. Administration of AE to animals with 4 h pylorus ligature ...

    • Inhibition of gastric acid secretion by a standardized aqueous extract of Cecropia glaziovii Sneth and underlying mechanism 

      Souccar, C. [UNIFESP]; Cysneiros, Roberta Monterazzo [UNIFESP]; Tanae, M. M. [UNIFESP]; Torres, L. M. B. [UNIFESP]; Lima-Landman, M. T. R. [UNIFESP]; Lapa, A. J. [UNIFESP] (Elsevier B.V., 2008-06-01)
      Cecropia glazioui Sneth (Cecroplaceae) is used in folk medicine in tropical and subtropical Latin America as cardiotonic, diuretic, hypotensive, anti-inflammatory and anti-asthmatic. the hypotensive/antihypertensive activity ...

    • Inhibition of gastric secretion by a water extract from Baccharis triptera, Mart 

      Gamberini, Maria T. [UNIFESP]; Skorupa, Ladislau Araújo; Souccar, Caden [UNIFESP]; Lapa, Antonio José [UNIFESP] (Instituto Oswaldo Cruz, Ministério da Saúde, 1991-01-01)
      Baccharus triptera Mart, is a widespread Compositae usedin Brazilian folk medicine to treat gastrointestinal disturbances, rheumatic disease, mild fever, diabetes and as an anti-helminthic. Water extract of small branches ...