Now showing items 1-5 of 5

    • ALTERED ACETYLCHOLINE RELEASE in the HIPPOCAMPUS of DYSTROPHIN-DEFICIENT MICE 

      Parames, S. F. [UNIFESP]; Coletta-Yudice, E. D. [UNIFESP]; Nogueira, F. M. [UNIFESP]; De Sousa, M. B. Nering [UNIFESP]; Hayashi, M. A. [UNIFESP]; Lima-Landman, M. T. R. [UNIFESP]; Lapa, A. J. [UNIFESP]; Souccar, C. [UNIFESP] (Elsevier B.V., 2014-06-06)
      Mild cognitive impairments have been described in one-third of patients with Duchenne muscle dystrophy (DMD). DMD is characterized by progressive and irreversible muscle degeneration caused by mutations in the dystrophin ...

    • INCREASED EXPRESSION of ACETYLCHOLINE RECEPTORS in the DIAPHRAGM MUSCLE of MDX MICE 

      Ghedini, Paulo C. [UNIFESP]; Viel, Tania A. [UNIFESP]; Honda, Luciana [UNIFESP]; Avellar, Maria Christina W. [UNIFESP]; Godinho, Rosely O. [UNIFESP]; Lima-Landman, Maria Teresa R. [UNIFESP]; Lapa, Antonio J. [UNIFESP]; Souccar, Caden [UNIFESP] (Wiley-Blackwell, 2008-12-01)
      The absence of dystrophin in Duchenne muscular dystrophy (DMD) and in the mutant mdx mouse causes muscle degeneration and disruption of the neuromuscular junction. Based on evidence from the denervation-like properties of ...

    • Mild dystrophic damage in the androgen-sensitive levator ani muscle of the mdx mouse 

      Souccar, C.; Goncalo, M. D.; Buck, H. D.; lima-Landman, MTR; Lapa, A. J. (Elsevier B.V., 2005-01-01)
      The time course of muscular dystrophy on the androgen-sensitive levator ani muscle was compared to that of the diaphragm of dystrophic (mdx) mice aged 1-20 months. Muscle growth, isometric contractile properties and ...

    • Morphological changes in the trigemino-rubral pathway in dystrophic (mdx) mice 

      Pinto, Magali Luci; Tokunaga, Heloisa Helena Vieira Olyntho; Souccar, Caden; Schoorlemmer, Gerhardus Hermanus Maria [UNIFESP]; Ribeiro da Silva Lapa, Rita de Cassia (Elsevier B.V., 2007-04-12)
      The lack of dystrophin that causes Duchenne muscle disease affects not only the muscles but also the central nervous system. Dystrophin-deficient mdx mice present changes in several brain fiber systems. We compared the ...

    • Quantitative changes of nicotinic receptors in the hippocampus of dystrophin-deficient mice 

      Ghedini, Paulo César [UNIFESP]; Avellar, Maria Christina Werneck [UNIFESP]; Lima, Thereza Cristina Monteiro de; Lima-Landman, Maria Teresa Riggio de [UNIFESP]; Lapa, Antonio José [UNIFESP]; Souccar, Caden [UNIFESP] (Elsevier B.V., 2012-11-05)
      Lack of dystrophin in Duchenne muscle dystrophy (DMD) and in the mutant mdx mouse results in progressive muscle degeneration, structural changes at the neuromuscular junction, and destabilization of the nicotinic acetylcholine ...