Now showing items 1-5 of 5

    • Expression of angiotensin I-converting enzymes and bradykinin B-2 receptors in mouse inner medullary-collecting duct cells 

      Redublo Quinto, Beata Marie [UNIFESP]; Camargo de Andrade, Maria Claudina [UNIFESP]; Ronchi, Fernanda Aparecida [UNIFESP]; Santos, Edson Lucas; Corrêa, Silvana Aparecida Alves [UNIFESP]; Shimuta, Suma Imura; Pesquero, Joao Bosco; Mortara, Renato Arruda; Casarini, Dulce Elena [UNIFESP] (Elsevier B.V., 2008-02-01)
      We described in mouse inner medullary-collecting duct cells (m1MCD-3) the somatic and the N-domain ACE synthesis and its interaction with the kallikrein-kinin system co-localized in the same cells. We purified two ACE forms ...

    • Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B-2 receptors 

      Scharfstein, J.; Schmitz, V; Morandi, V; Capella, MMA; Lima, APCA; Morrot, A.; Juliano, Luiz [UNIFESP]; Muller-Esterl, W. (Rockefeller Univ Press, 2000-11-06)
      The parasitic protozoan Trypanosoma cruzi employs multiple molecular strategies to invade a broad range of nonphagocytic cells. Here we demonstrate that the invasion of human primary umbilical vein endothelial cells (HUVECs) ...

    • IL-4 and IL-13 inhibit IL-1 beta and TNF-alpha induced kinin B-1 and B-2 receptors through a STAT6-dependent mechanism 

      Souza, P. P. C.; Brechter, A. B.; Reis, R. I. [UNIFESP]; Costa, C. A. S.; Lundberg, P.; Lerner, U. H. (Wiley-Blackwell, 2013-05-01)
      Background and Purpose Bone resorption induced by interleukin-1 (IL-1) and tumour necrosis factor (TNF-) is synergistically potentiated by kinins, partially due to enhanced kinin receptor expression. Inflammation-induced ...

    • Leptin deficiency leads to the regulation of kinin receptors expression in mice 

      Abe, Karina Camasmie; Silva Mori, Marcelo Alves da; Pesquero, Joao Bosco (Elsevier B.V., 2007-02-01)
      Kinins are vasoactive and pro-inflammatory peptides generated by the cleavage of the kininogen by kallikreins. Two kinin receptors have been described and denominated B1 and B2. Obesity frequently accompanies other ...

    • Vascular Kinin B-1 and B-2 Receptors Determine Endothelial Dysfunction through Neuronal Nitric oxide Synthase 

      Mesquita, Thassio R. R.; Campos-Mota, Gianne P.; Lemos, Virginia S.; Cruz, Jader S.; de Jesus, Itamar C. G.; Camargo, Enilton A.; Pesquero, Jorge L.; Pesquero, Joao B. [UNIFESP]; Capettini, Luciano Dos Santos A.; Lauton-Santos, Sandra (Frontiers Media Sa, 2017)
      B-1- and B-2-kinin receptors are G protein-coupled receptors that play an important role in the vascular function. Therefore, the present study was designed to evaluate the participation of kinin receptors in the acetylcholine ...