Now showing items 1-2 of 2

    • Kinetic studies on clavulanic acid degradation 

      Bersanetti, Patricia A.; Almeida, Renata M R G; Barboza, Marlei; Araujo, Maria Lucia G; Hokka, Carlos Osamu (Elsevier B.V., 2005-03-01)
      Clavulanic acid (CA), a potent beta-lactamase inhibitor, is very sensitive to pH and temperature. It is produced by Streptomyces clavuligerus and to optimize both the fermentation step and the downstream process, the ...

    • Substrate specificity and the effect of calcium on Trypanosomabrucei metacaspase 2 

      Machado, Mauricio F. M. [UNIFESP]; Marcondes, Marcelo F. [UNIFESP]; Juliano, Maria A. [UNIFESP]; McLuskey, Karen; Mottram, Jeremy C.; Moss, Catherine X.; Juliano, Luiz [UNIFESP]; Oliveira, Vitor [UNIFESP] (Wiley-Blackwell, 2013-06-01)
      Metacaspases are cysteine peptidases found only in yeast, plants and lower eukaryotes, including the protozoa. To investigate the extended substrate specificity and effects of Ca2+ on the activation of these enzymes, ...