Browsing by Subject "immunosuppression"

Now showing items 1-10 of 21

    • Avaliação da tolerabilidade do micofenolato de sódio com revestimento entérico em receptores de transplante renal 

      Hiramoto, Liliane Lumi [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-12-31)
      Introduction: The enteric coated mycophenolate sodium (EC-MPS) is an antiproliferative prodrug which acts in the biosynthesis of purines. A major limitation of the EC-MPS is the occurrence of gastrointestinal adverse events ...

    • Changes in lymphocyte phenotype and increased skin allograft survival after FTY720+FK506 therapy 

      Lopes, Camila Takáo [UNIFESP]; Silva, Léa B. L.; Cury, Patricia M.; Burdmann, Emmanuel A.; Bueno, Valquiria [UNIFESP] (Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, 2008-01-01)
      The development of new drugs to be associated with calcineurin inhibitors and promote additional immunosuppression with fewer side effects is the goal in transplantation. FTY720 is a new synthetic compound which presents ...

    • Circadian and time-dependent variability in tacrolimus pharmacokinetics 

      Park, Sung-In; Felipe, Claudia R.; Pinheiro-Machado, Paula G.; Garcia, Riberto; Tedesco-Silva, Helio; Medina-Pestana, Jose O. (Blackwell Publishing, 2007-04-01)
      Tacrolimus (TAC) is considered a critical dose drug. the purpose of our study was to investigate circadian and time-dependent changes in TAC pharmacokinetics over the first year after kidney transplantation. Pharmacokinetic ...

    • Concentration-controlled use of sirolimus associated with reduced exposure of cyclosporine in black recipients of primarily living renal allograft donors: 12-month results 

      Ferreira, A. N.; Machado, P. G.; Felipe, C. R.; Motegi, S. A.; Hosaka, B. H.; Tanaka, M. K.; Kamura, L. A.; Park, S. I.; Garcia, R.; Franco, M.; Alfieri, F.; Casarini, D. E.; Tedesco-Silva, H.; Medina-Pestana, J. O. (Blackwell Publishing, 2005-10-01)
      Aim: This study was designed to identify optimal therapeutic sirolimus (SRL) concentrations in black kidney transplant recipients on reduced cyclosporine (CsA) exposure and prednisone.Methods: Seventy patients (64 living/six ...

    • The diagnostic yield and complications of open lung biopsies in kidney transplant patients with pulmonary disease 

      Tomotani, Daniere Yurie Vieira [UNIFESP]; Bafi, Antonio Tonete [UNIFESP]; Pacheco, Eduardo Souza [UNIFESP]; Sandes-Freitas, Taina Veras de [UNIFESP; Viana, Laila Almeida [UNIFESP]; Pontes, Edgar Porto de Oliveira [UNIFESP]; Tamura, Nikkei [UNIFESP]; Tedesco-Silva Junior, Hélio [UNIFESP]; Machado, Flavia Ribeiro [UNIFESP]; Freitas, Flavio Geraldo Rezende [UNIFESP] (Pioneer Bioscience Publ Co, 2017)
      Background: The purpose of this study was to assess the efficacy of open lung biopsy (OLB) in determining the specific diagnosis and the related complications in patients with undiagnosed diffuse pulmonary infiltrates. ...

    • The Emerging Role of Brazil in Clinical Trial Conduct for Transplantation 

      Tedesco-Silva Junior, Hélio [UNIFESP]; Felipe, Claudia Rosso [UNIFESP]; Abbud-Filho, M.; Garcia, V.; Medina-Pestana, J. O. [UNIFESP] (Wiley-Blackwell, 2011-07-01)
      Brazil is a country with over 190 000 000 inhabitants and a health system composed of a large public, government managed system. Between 1999 and 2010 the number of deceased donors increased by 161%, from 3.8 to 9.9 pmp, ...

    • Evaluation of stem cell administration in a model of kidney ischemia-reperfusion injury 

      Lucas da Silva, Ua Bueno; Bomm Palma, Patricia Viana; Cury, Patricia Maluf; Bueno, Valquiria [UNIFESP] (Elsevier B.V., 2007-12-15)
      Ischemia-reperfusion injury is a common early event in kidney transplantation and contributes to a delay in organ function. Acute tubular necrosis, impaired kidney function and organ leukocyte infiltration are the major ...

    • Fungal infection due to fusarium (spp) in children with refractory hematologic malignancies 

      Mangini, C.; Camargo, B. de (Wiley-Blackwell, 1999-02-01)

    • Human papillomavirus detected in viral warts of renal transplant recipients 

      Martelli-Marzagao, F. [UNIFESP]; Santos Junior, G. F.; Ogawa, M. M. [UNIFESP]; Enokihara, M. M. S. S. [UNIFESP]; Porro, A. M. [UNIFESP]; Tomimori, J. [UNIFESP] (Wiley-Blackwell, 2016)
      ObjectivesFew studies have been conducted in South America regarding the detection and genotyping of human papillomavirus (HPV) in viral warts of renal transplant recipients (RTRs). The characterization of the population ...

    • Human papillomavirus detected in viral warts of renal transplant recipients 

      Martelli-Marzagao, F. [UNIFESP]; Santos Junior, G. F.; Ogawa, M. M. [UNIFESP]; Enokihara, M. M. S. S. [UNIFESP]; Porro, A. M. [UNIFESP]; Tomimori, J. [UNIFESP] (Wiley-Blackwell, 2016)
      ObjectivesFew studies have been conducted in South America regarding the detection and genotyping of human papillomavirus (HPV) in viral warts of renal transplant recipients (RTRs). The characterization of the population ...