Browsing by Subject "hypertension"
Now showing items 1-10 of 116
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An 18-Week, Prospective, Randomized, Double-Blind, Multicenter Study of Amlodipine/Ramipril Combination Versus Amlodipine Monotherapy in the Treatment of Hypertension: the Assessment of Combination Therapy of Amlodipine/Ramipril (ATAR) Study
(Elsevier B.V., 2008-09-01)Background: A combination of antihypertensive agents of different drug classes in a fixed-dose combination (FDC) may offer advantages in terms of efficacy, tolerability, and treatment compliance. Combination of a calcium ...
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alpha(2)-adrenergic receptors are not required for central anti-hypertensive action of moxonidine in mice
(Elsevier B.V., 2000-04-17)In the mouse medulla oblongata, we characterized binding properties and functional responses of two recognition sites for imidazoline compounds: I-1-imidazoline and alpha(2)-adrenergic receptors. the mouse medulla expresses ...
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Altered Balance of gamma-Aminobutyric Acidergic and Glutamatergic Afferent Inputs in Rostral Ventrolateral Medulla-Projecting Neurons in the Paraventricular Nucleus of the Hypothalamus of Renovascular Hypertensive Rats
(Wiley-Blackwell, 2010-03-01)An imbalance of excitatory and inhibitory functions has been shown to contribute to numerous pathological disorders. Accumulating evidence supports the idea that a change in hypothalamic gamma-aminobutyric acid (GABA)-ergic ...
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Amlodipine 2.5 mg once daily in older hypertensives: a Brazilian multi-centre study
(Lippincott Williams & Wilkins, 2004-04-01)Objectives the use of low-dose amlodipine has not yet been well established in the elderly. This study therefore aimed to evaluate the efficacy and tolerability of low-dose amlodipine in elderly patients with Joint National ...
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Angiotensin II antagonists - therapeutic benefits spanning the cardiovascular disease continuum from hypertension to heart failure and diabetic nephropathy
(Librapharm, 2006-01-01)Background: the cardiovascular benefits of angiotensin II antagonists (AIIAs) have been evaluated not only in terms of their ability to lower blood pressure but also on their ability to prevent strokes, cardiac events, and ...
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Angiotensin II antagonists for hypertension: Are there differences in efficacy?
(Elsevier B.V., 2000-04-01)We compared the antihypertensive efficacy of available drugs in the new angiotensin-II-antagonist (AIIA) class. the antihypertensive efficacy of losartan, valsartan, irbesartan, and candesartan was evaluated from randomized ...
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Antihypertensive effects of central ablations in spontaneously hypertensive rats
(Amer Physiological Soc, 2009-06-01)Moreira TS, Takakura AC, Colombari E, Menani JV. Antihypertensive effects of central ablations in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol 296: R1797-R1806, 2009. First published April 1, ...
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Antihypertensive responses elicited by central moxonidine in rats: Possible role of nitric oxide
(Lippincott Williams & Wilkins, 2006-06-01)In the present study, we investigated the effects of pretreatment with N-G-nitro-L-arginine methyl ester (L-NAME) (nitric oxide synthase inhibitor) injected intravenously (IV) on the hypotension, bradycardia, and vasodilation ...
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Arterial hypertension following renal transplantation in children - a short-term study
(Springer, 2003-12-01)Systemic arterial hypertension is a common complication among transplanted patients. the objective of this study was to investigate the risk factors for arterial hypertension after kidney transplantation in children. A ...
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Atividade vasomotora simpatica renal e esplâncnica em um modelo de hipertensão por inbição da sintese de oxido nitrico
(Universidade Federal de São Paulo (UNIFESP), 2016-02-29)Systemic hypertension is a multifactorial disease. Among several factors that contributes to the increase in blood pressure, it highlights the deficiency of nitric oxide (NO) and changes in sympathetic vasomotor activity ...
