Browsing by Subject "glycosylation"
Now showing items 1-5 of 5
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Analysis of the Ontogenetic Variation in the Venom Proteome/Peptidome of Bothrops jararaca Reveals Different Strategies to Deal with Prey
(Amer Chemical Soc, 2010-05-01)Previous studies have demonstrated that the pharmacological activities displayed by Bothrops jararaca venom undergo a significant ontogenetic shift. Variation in the venom proteome is a well-documented phenomenon; however, ...
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Differential Gene Transcription of Extracellular Matrix Components in Response to In Vivo Corneal Crosslinking (CXL) in Rabbit Corneas
(Assoc Research Vision Ophthalmology Inc, 2017)Purpose: We studied changes in gene transcription after corneal crosslinking (CXL) in the rabbit cornea in vivo and identified potential molecular signaling pathways. Methods: A total of 15 corneas of eight male New-Zealand-White ...
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The effect of post-translational modifications on the hemorrhagic activity of snake venom metalloproteinases
(Elsevier B.V., 2004-05-01)Metalloproteinases (MPs) are Zn+-dependent endoproteolytic enzymes, abundant in crotalid and viperid snake venoms. Most snake venom metalloproteinases (svMPs) are active on extracellular matrix components and this effect ...
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The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles
(Elsevier B.V., 2001-05-01)Trypanosoma cruzi expresses at its surface large amounts of mucin-like glycoproteins. the T. cruzi mucins (TcMUC), a group of highly glycosylated GPI-anchored proteins rich in Thr, Ser, and Pro residues, are expressed in ...
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TrkA glycosylation regulates receptor localization and activity
(Wiley-Blackwell, 1999-05-01)The human nerve growth factor receptor (TrkA) contains four potential N-glycosylation sites that are highly conserved within the Trk family of neurotrophin receptors, and nine additional sites that are less well conserved. ...