Browsing by Subject "glutathione"

Now showing items 1-10 of 11

    • Absence of oxidative stress following paradoxical sleep deprivation in rats 

      DAlmeida, V; Hipolide, D. C.; Azzalis, L. A.; Lobo, L. L.; Junqueira, VBC; Tufik, Sergio [UNIFESP] (Elsevier B.V., 1997-10-10)
      Paradoxical sleep deprivation was performed on rats using platform technique to investigate the oxidative process associated with it. Levels of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), total ...

    • Acute effects of inhalable particles on the frog palate mucociliary epithelium 

      Macchione, Mariangela; Oliveira, Alexandre P.; Gallafrio, Cristina T.; Muchão, Fabio B.; Obara, Marcos T.; Guimarães, Eliane T.; Artaxo, Paulo; King, Malcolm; Lorenzi-Filho, Geraldo; Junqueira, Virginia Berlanga Campos [UNIFESP]; Saldiva, Paulo Hilário Nascimento (Us Dept Health Human Sciences Public Health Science, 1999-10-01)
      This work was designed to evaluate the toxicity of inhalable particles less than or equal to 10 pm in aerodynamic diameter (PM10) collected from the urban air in São Paulo, Brazil, to the mucociliary apparatus using the ...

    • Age-dependent detection of erythrocytes glucose-6-phosphate dehydrogenase and its correlation with oxidative stress 

      Maurya, Pawan Kumar [UNIFESP]; Kumar, Prabhanshu; Chandra, Pranjal (Taylor & Francis Ltd, 2016)
      Context: Glucose-6-phosphate dehydrogenase (G6PD) is an important enzyme of hexose monophosphate shunt, involved in the biosynthesis of reduced nicotinamide adenine dinucleotide phosphate hydrogen (NADPH). Objective: This ...

    • Association of polymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease 

      Marques Souza Oliveira, Claudia Pinto; Stefano, Jose Tadeu; Cavaleiro, Ana Mercedes; Henriques Zanella Fortes, Maria Angela; Vieira, Suzana Maria; Rodrigues Lima, Vicencia Mara; Santos, Telma Eugenio; Santos, Virginia Nascimento [UNIFESP]; Farias de Azevedo Salgado, Ana Lucia [UNIFESP]; Parise, Edson Roberto [UNIFESP]; Ferreira Alves, Venancio Avancini; Carrilho, Flair Jose; Correa-Giannella, Maria Lucia (Wiley-Blackwell, 2010-02-01)
      Background and Aims: Although the metabolic risk factors for non-alcoholic fatty liver disease (NAFLD) progression have been recognized, the role of genetic susceptibility remains a field to be explored. the aim of this ...

    • Blood oxidative stress markers in Gaucher disease patients 

      Roversi, F. M.; Galdieri, L. C.; Grego, BHC; Souza, F. G.; Micheletti, C.; Martins, A. M.; D'Almeida, V (Elsevier B.V., 2006-02-01)
      Background: Gaucher disease (GD) is the most common glycosphingolipidosis resulting in accumulation of glucoceramide. the most effective treatment for this disease is enzyme replacement therapy (ERT) which involves recombinant ...

    • Development of a Sustained-release System for Nitric Oxide Delivery using Alginate/Chitosan Nanoparticles 

      Marcato, Priscyla D.; Adami, Leonardo F.; Barbosa, Raquel de Melo; Melo, Patricia S.; Ferreira, Iasmin R.; Paula, Larissa de; Duran, Nelson; Seabra, Amedea Barozzi [UNIFESP] (Bentham Science Publ Ltd, 2013-02-01)
      Free radical nitric oxide (NO) has been known to interact with various physiological processes, such as wound repair processes and control of vascular tone. However, NO is an unstable molecule and the development of NO ...

    • Dietary riboflavin restriction and chronic hemin administration does not alter brain function in rats: The importance of vitamin homeostasis in the brain 

      DalPai, Janise [UNIFESP]; Borges, Andrea Aurélio [UNIFESP]; Grassl, Christian [UNIFESP]; Favero Filho, Luiz Antonio [UNIFESP]; Xavier, Gilberto Fernando [UNIFESP]; Junqueira, Virginia Berlanga Campos [UNIFESP]; Lopes, Antonio Carlos [UNIFESP]; Coimbra, Cicero Galli [UNIFESP]; Sinigaglia-Coimbra, Rita [UNIFESP] (New Century Health Publishers, Llc, 2007-11-01)
      Vitamin B2 deficiency associated with normal dietary intake has been reported inpatients with Parkinson disease (PD), suggesting impaired absorption of this micronutrient. Elevated red meat consumption was thought to ...

    • Influence of protein phosphatase inhibitors on HL60 cells death induction by dehydrocrotonin 

      Freire, ACG; Assis, C. F. de; Frick, A. O.; Melo, P. D.; Haun, M.; Aoyama, H.; Duran, N.; Sauer, M. M.; Kallas, E. G.; Ferreira, C. V. (Elsevier B.V., 2003-09-01)
      Oxidative stress can be involved in several cellular responses, such as differentiation, apoptosis and necrosis. Dehydrocrotonin (DCTN, diterpene lactone) from Croton cajucara, Brazilian medicinal plant, slightly induced ...

    • Melatonin treatment does not prevent decreases in brain glutathione levels induced by sleep deprivation 

      D'Almedia, V; Hipolide, D. C.; Lobo, L. L.; Oliveira, A. C. de; Nobrega, J. N.; Tufik, S. (Elsevier B.V., 2000-03-03)
      Recent findings from this laboratory revealed that sleep deprivation reduces total glutathione (GSH) levels in hypothalamus, suggesting an increased vulnerability to oxidative damage. Since melatonin has been shown to ...

    • Sleep deprivation induces brain region-specific decreases in glutathione levels 

      D'Almeida, V; Lobo, L. L.; Hipolide, D. C.; Oliveira, A. C. de; Nobrega, J. N.; Tufik, S. (Lippincott Williams & Wilkins, 1998-08-24)
      RATS were deprived of sleep for 96 h by the platform technique and total glutathione (GSH tau) levels were measured in seven different brain areas. Glutathione levels were found to be significantly reduced in the hypothalamus ...