Browsing by Subject "glutamate"
Now showing items 1-9 of 9
-
Ascorbic acid and alpha-tocopherol attenuate methylmalonic acid-induced convulsions
(Lippincott Williams & Wilkins, 1999-07-13)THE effects of chronic administration of alpha-tocopherol or melatonin, or acute ascorbic acid administration on the convulsant action of methylmalonic acid (MMA) were investigated in adult male rats. Animals were chronically ...
-
Differential baroreceptor modulation mediated by the ventrolateral medulla
(Elsevier B.V., 2006-06-30)Previous studies have shown that pharmacological stimulation of a region denominated caudal pressor area (CPA), located in the caudal end of the ventrolateral medulla, induces increases in arterial blood pressure (BP). the ...
-
Glutamate levels in cerebrospinal fluid and triptans overuse in chronic migraine
(Blackwell Publishing, 2007-06-01)Objective.-Chronic migraine (CM) is a common disorder, affecting 2% to 3% of the general population. Glutamate is implicated in cortical spreading depression, trigeminovascular activation, central sensitization, and may ...
-
The Integration of the Glutamatergic and the White Matter Hypotheses of Schizophrenia's Etiology
(Bentham Science Publ Ltd, 2012-03-01)Background: schizophrenia's endophenotipic profile is not only generally complex, but often varies from case to case. The perspective of trying to define specific anatomic correlates of the syndrome has led to disappointing ...
-
Methylmalonate impairs mitochondrial respiration supported by NADH-linked substrates: Involvement of mitochondrial glutamate metabolism
(Wiley-Blackwell, 2012-06-01)The neurodegeneration that occurs in methylmalonic acidemia is proposed to be associated with impairment of mitochondrial oxidative metabolism resulting from methylmalonate (MMA) accumulation. the present study evaluated ...
-
Resistance to ethanol sensitization is associated with increased NMDA receptor binding in specific brain areas
(Elsevier B.V., 2002-05-03)Co-administration of N-methyl- D-aspartate (NMDA) receptor antagonists is known to block the development of behavioral sensitization to ethanol and other psycho stimulants. Since ethanol sensitization in mice does not occur ...
-
Role of carbon monoxide in L-glutamate-induced cardiovascular responses in nucleus tractus solitarius of conscious rats
(Elsevier B.V., 1999-04-10)Heme oxygenase degrades heme to form carbon monoxide. It has been reported that heme oxygenase-derived carbon monoxide may interact with L-glutamate (L-Glu) receptors in the nucleus tractus solitarius (NTS). Integrative ...
-
Rostral ventrolateral medulla - A source of sympathetic activation in rats subjected to long-term treatment with L-NAME
(Lippincott Williams & Wilkins, 1999-10-01)The major aim of the present study was to evaluate the role of the rostral ventrolateral medulla (RVLM) in the maintenance of hypertension in rats subjected to long-term treatment with N-G-nitro-L-arginine methyl ester ...
