Now showing items 1-7 of 7

    • Getting too sweet: galectin-1 dysregulation in gestational diabetes mellitus 

      Blois, Sandra M.; Gueuvoghlanian-Silva, Barbara Y. [UNIFESP]; Tirado-Gonzalez, Irene; Torloni, Maria Regina [UNIFESP]; Freitag, Nancy; Mattar, Rosiane [UNIFESP]; Conrad, Melanie L.; Unverdorben, Laura; Barrientos, Gabriela; Knabl, Julia; Toldi, Gergely; Molvarec, Attila; Rose, Matthias; Markert, Udo R.; Jeschke, Udo; Daher, Silvia [UNIFESP] (Oxford Univ Press, 2014-07-01)
      Galectin-1 (gal-1) is a prototype carbohydrate-binding protein, whose dysregulation is associated with adverse pregnancy outcomes such as spontaneous abortion and pre-eclampsia. Furthermore, it is known that faulty gal-1 ...

    • Impaired Treg and NK cells profile in overweight women with gestational diabetes mellitus 

      Lobo, Thalita Frutuoso [UNIFESP]; Borges, Cannila de Moraes [UNIFESP]; Mattar, Rosiane [UNIFESP]; Gomes, Caio Perez [UNIFESP]; Angelo, Ana Geisa Santos de [UNIFESP]; Pendeloski, Karen Priscilla Tezotto [UNIFESP]; Daher, Silvia [UNIFESP] (Wiley, 2018)
      Problem: Maternal obesity is frequently associated with gestational diabetes mellitus (GDM), and immunological mechanisms seem to be involved in the physiopathology of these conditions. The aim of this study was to ...

    • Insulin analogues in the treatment of diabetes in pregnancy 

      Negrato, Carlos Antonio; Montenegro Junior, Renan Magalhães; Von Kostrisch, Lilia Maria; Guedes, Maria Fatima; Mattar, Rosiane [UNIFESP]; Gomes, Marilia de Brito (Sociedade Brasileira de Endocrinologia e Metabologia, 2012-10-01)
      Pregnancy affects both maternal and fetal metabolism, and even in non-diabetic women, it exerts a diabetogenic effect. Among pregnant women, 2% to 14% develop gestational diabetes. Pregnancy can also occur in women with ...

    • Periodontal disease in gestational and type 1 diabetes mellitus pregnant women 

      Ruiz, D. R. [UNIFESP]; Romito, G. A.; Dib, S. A. [UNIFESP] (Wiley-Blackwell, 2011-07-01)
      Objective:The present study evaluated the relationship between periodontal disease and its clinical variables in Brazilian non-diabetic pregnant women (C), gestational diabetes mellitus (GDM), or type 1 diabetes mellitus ...

    • Prepregnancy BMI and the risk of gestational diabetes: a systematic review of the literature with meta-analysis 

      Torloni, M. R. [UNIFESP]; Betran, A. P.; Horta, B. L.; Nakamura, M. U. [UNIFESP]; Atallah, A. N. [UNIFESP]; Moron, A. F. [UNIFESP]; Valente, O. [UNIFESP] (Wiley-Blackwell, 2009-03-01)
      The objective of this study is to assess and quantify the risk for gestational diabetes mellitus (GDM) according to prepregnancy maternal body mass index (BMI). the design is a systematic review of observational studies ...

    • Progesterone induces apoptosis of insulin-secreting cells: insights into the molecular mechanism 

      Nunes, V. A.; Portioli-Sanches, E. P.; Rosim, M. P.; Araujo, M. S. [UNIFESP]; Praxedes-Garcia, P. [UNIFESP]; Valle, M. M. R.; Roma, L. P.; Hahn, C.; Gurgul-Convey, E.; Lenzen, S.; Azevedo-Martins, A. K. (Bioscientifica Ltd, 2014-05-01)
      Progesterone has been associated with the development of gestational diabetes (GD) due to the enhancement of insulin resistance. As b-cell apoptosis participates in type 1 and type 2 diabetes pathophysiology, we proposed ...

    • Vitamin D and gestational diabetes: an update 

      Joergensen, Jan S.; Lamont, Ronald F.; Torloni, Maria R. [UNIFESP] (Lippincott Williams & Wilkins, 2014-07-01)
      Purpose of reviewVitamin D status (which is involved in glucose homeostasis) is related to gestational diabetes mellitus (GDM). GDM is characterized by increased resistance to and impaired secretion of insulin and results ...