Now showing items 1-10 of 23

    • Allele frequency of ADH2 and ALDH2 among Brazilians of different ethnic groups 

      Santos, B. R.; Monteiro, M. G.; Thomasson, H. R. (Elsevier B.V., 1997-05-01)
      We determined the genotypes of the alcohol dehydrogenase (ALDH) and aldehyde dehydrogenase (ALDH2) loci of different ethnic groups living in Brazil, using saliva DNA amplified by PCR and allele-specific oligonucleotides. ...

    • Análise de polimorfismo nos genes do colágeno 1a1 e do receptor de vitamina d em mulheres em terapia substitutiva com estrogênios 

      Pereira, Elenir Monteiro de Santana [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014-06-25)
      Introduction: The increase of the life expectancy in the last 60 years, makes women spend one-third of their lifetime in climacteric period. The hormonal replacement in the post-menopause, seems to bring many benefits such ...

    • Análise de polimorfismo nos genes do receptor de estrogênio alpha – ERα (HaeIII e MspI) em mulheres em terapia substitutiva com estrogênios 

      Taborda, Ana Maria de Oliveira [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014-06-25)
      Introduction: The increase of the life expectancy in the last 60 years, makes women spend one-third of their lifetime in climacteric period. The hormonal replacement in the post-menopause, seems to bring many benefits such ...

    • Avaliação de polimorfismo do gene vdr e valores séricos de vitamina d no diabetes mellitus gestacional 

      Siqueira, Thais Walverde [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-08-31)
      Introduction: The pathophysiology of Gestational Diabetes Mellitus (GDM) involves the participation of many factors and mechanisms such as insulin resistance and inflammation. Vitamin D is identified as a critical element ...

    • Characterization of enterotoxigenic Escherichia coli by random amplification of polymorphic DNA 

      Pacheco, ABF; Guth, BEC; deAlmeida, D. F.; Ferreira, LCS (Elsevier B.V., 1996-03-01)
      Two enterotoxigenic Escherichia coli (ETEC) strains (H10407 and 4011-1) were characterized by random amplification of polymorphic DNA (RAPD) profiles using 10-mer oligonucleotides with diverse GC content, All tested primers ...

    • Diversity in Paracoccidioides brasiliensis. the PbGP43 gene as a genetic marker 

      Puccia, Rosana [UNIFESP]; McEwen, Juan G.; Cisalpino, Patricia Silva (Springer, 2008-04-01)
      Paracoccidioides brasiliensis is a temperature-dependent dimorphic fungus and the agent of paracoccidioidomycosis (PCM), which is prevalent in rural workers of Latin American countries. Until a decade ago, most of the ...

    • Estudo da frequência dos alelos de HLA-DRB1 em pacientes brasileiros com artrite reumatoide 

      Usnayo, Magali Justina Gómez; Andrade, Luiz Eduardo Coelho [UNIFESP]; Alarcon, Renata Trigueirinho [UNIFESP]; Oliveira, Juliana Cardoso; Silva, Gustavo Milson Fabrício; Bendet, Izidro; Burlingame, Rufus; Porto, Luis Cristóvão; Pinheiro, Geraldo da Rocha Castelar (Sociedade Brasileira de Reumatologia, 2011-10-01)
      The HLA-DRB1 alleles encoding an amino acid sequence (QKRAA/QRRAA/RRRAA) at position 70 74 of the third hypervariable region of the β1 chain of the HLA-DRB1 gene, called shared epitope (SE), are associated with increased ...

    • Evaluation of Demographic, Clinical Characteristics, and Genetic Polymorphism as Risk Factors for Pelvic Organ Prolapse in Brazilian Women 

      Martins, Karina de Falco [UNIFESP]; Katalin de Jarmy-Di Bella, Zsuzsanna Ilona [UNIFESP]; Rodrigues Maciel da Fonseca, Andrea Moura; Castro, Rodrigo Aquino [UNIFESP]; Cotrim Guerreiro da Silva, Ismael Dale [UNIFESP]; Batista Castello Girao, Manoel Joao [UNIFESP]; Ferreira Sartori, Marair Gracio [UNIFESP] (Wiley-Blackwell, 2011-01-01)
      Objective: Verify the association between genital prolapse, other risk factors and a polymorphism in exon 31 of the collagen III-a1 gene (COL3A1). Setting: the etiology of genital prolapse is multifactorial, and genetic ...

    • Exposure to pesticides and heterozygote genotype of GSTP1-Alw26I are associated to Parkinson's disease 

      Longo, Gabriela S.; Pinhel, Marcela Augusta de Souza; Sado, Caroline L.; Gregorio, Michele L.; Amorim, Gisele S.; Florim, Greiciane S.; Mazeti, Camila M.; Martins, Denise P.; Oliveira, Fabio N.; Tognola, Waldir A.; Nakazone, Marcelo A.; Souza, Dorotéia Rossi Silva (Academia Brasileira de Neurologia - ABNEURO, 2013-07-01)
      Objective This study aimed to analyze the frequency of GSTP1-Alw26I polymorphism and to estimate its association with toxic substances in Parkinson's disease (PD). Methods A study group with 154 patients - subdivided into ...

    • Glutathione S-transferase polymorphisms in osteosarcoma patients 

      Salinas-Souza, Carolina [UNIFESP]; Petrilli, Antonio S.; Toledo, Silvia R. C. de [UNIFESP] (Lippincott Williams & Wilkins, 2010-08-01)
      Background Osteosarcoma is the most common malignant bone tumor in children and adolescents. Multidrug resistance and poor clinical outcome are the problems that still affect osteosarcoma patients. the glutathione S-transferase ...