Browsing by Subject "gene expression"
Now showing items 1-10 of 54
-
Adenoviral-mediated gene transfer to the filtering bleb in rabbits
(Lippincott Williams & Wilkins, 2001-12-01)Purpose: To determine if genes can be transferred to fibroblasts in the filtering bleb using adenoviral vectors. Materials and Methods: Twelve New Zealand albino rabbits underwent bilateral full-thickness sclerostomies. ...
-
Affected and non-affected skin fibroblasts from systemic sclerosis patients share a gene expression profile deviated from the one observed in healthy individuals
(Clinical & Exper Rheumatology, 2008-09-01)ObjectivesTo evaluate the gene expression profile of fibroblasts from affected and non-affected skin of systemic sclerosis (SSc) patients and from controls.Materials and methodsLabeled cDNA from fibroblast cultures from ...
-
Analysis of HSPA8 and HSPA9 mRNA Expression and Promoter Methylation in the Brain and Blood of Alzheimer's Disease Patients
(Ios Press, 2014-01-01)Alzheimer's disease (AD) is the most common form of dementia in elderly. Chaperones may have a crucial role in AD due to their involvement in protein quality control, folding, and degradation. in this study, we investigated ...
-
Análise da expressão de genes relacionados à depressão em sangue de crianças e adolescentes deprimidos
(Universidade Federal de São Paulo (UNIFESP), 2015-03-31)Major Depressive Disorder (MDD) is a complex disorder caused by interactions among genetic and environmental factors, affecting several biological systems. Evidences have shown that the majority of the first depressive ...
-
Análise da expressão do gene kiaa1549-braf e das mutações dos genes idh1 e idh2 em amostras de astrocitomas de baixo grau da infância
(Universidade Federal de São Paulo (UNIFESP), 2013-06-26)Low-grade astrocytomas comprise about 30% of the central nervous system tumors in children. Several investigations have looked for the correlation between the KIAA1549-BRAF gene fusions and mutations at IDH1 and IDH2 genes ...
-
Análise da expressão do TFDP1 no endométrio tópico de mulheres com endometriose
(Universidade Federal de São Paulo (UNIFESP), 2016-05-04)Introduction: one of the researches fields of the ethiopathogenesis of endometriosis aims to identify endometrial disorders as the origin of the disease. Changes in expression of proteins related to cell adhesion, collagenases, ...
-
Análise da sinalização do hormônio tireoideano em cérebros humanos: possíveis correlações entre o hormônio tireoideano e a depressão
(Universidade Federal de São Paulo (UNIFESP), 2016-10-25)Thyroid hormones (TH) are essential for the maintenance of the central nervous system (CNS). An abnormal hormonal dynamics is related to psychiatric disorders such as depression. Among the different types, Major Depressive ...
-
Annexin-A1 gene expression during liver development and post-translation modification after experimental endotoxemia
(Birkhauser Verlag Ag, 2008-03-01)Objective and design: We have previously reported a role for annexin-A1 in liver proliferation and tumorogenicity as well as its action as an acute phase protein in a model of endotoxemia in interleukin-6 null mice.Material ...
-
Avaliação da expressão gênica das vias de sinalização de insulina em células da granulosa provenientes de mulheres eutróficas e obesas com síndrome dos ovários policísticos em ciclos de fertilização in vitro
(Universidade Federal de São Paulo (UNIFESP), 2015-11-27)Objective: To evaluate granulosa cell gene expression from insulin signaling pathway of Polycystic Ovarian Syndrome (PCOS) patients after In Vitro Fertilization (IVF) and compare the granulosa gene expression activity ...
-
Busca por potenciais marcadores genéticos nas fases iniciais da esquizofrenia
(Universidade Federal de São Paulo (UNIFESP), 2016-10-25)Schizophrenia is a severe and disabling psychiatric disorder that affects about 1% of the population. It is a complex disease characterized by the change in multiple genes of susceptibility. Once schizophrenia has been ...
