Now showing items 1-6 of 6

    • A Carbohydrate Moiety of Secreted Stage-Specific Glycoprotein 4 Participates in Host Cell Invasion by Trypanosoma cruzi Extracellular Amastigotes 

      Florentino, Pilar T. V.; Real, Fernando; Orikaza, Cristina Mary [UNIFESP]; Cunha, Julia P. C. da; Vitorino, Francisca N. L.; Cordero, Esteban M.; Sobreira, Tiago J. P.; Mortara, Renato Arruda [UNIFESP] (Frontiers Media Sa, 2018)
      Trypanosoma cruzi is the etiologic agent of Chagas' disease. It is known that amastigotes derived from trypomastigotes in the extracellular milieu are infective in vitro and in vivo. Extracellular amastigotes (EAs) have a ...

    • Expression of galectin-3 in gastric adenocarcinoma 

      Gomes, Thiago Simao [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Forones, Nora Manoukian [UNIFESP]; Lima, Flavio de Oliveira [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP] (Indian Council Medical Res, 2014-07-01)
      Background & objectives: Galectin-3 a member of the galectin family is an endogenous beta-galactoside binding lectin. It has been found to be associated with cell adhesion, recognition, proliferation, differentiation, ...

    • Galectin-3: A Friend but Not a Foe during Trypanosoma cruzi Experimental Infection 

      da Silva, Aline A.; Teixeira, Thaise L.; Teixeira, Samuel C.; Machado, Fabricio C. [UNIFESP]; dos Santos, Marlus A.; Tomiosso, Tatiana C.; Tavares, Paula C. B.; e Silva Brigido, Rebecca T.; Martins, Flavia Alves; de Lira Silva, Nadjania S. [UNIFESP]; Rodrigues, Cassiano C.; Roque-Barreira, Maria C.; Mortara, Renato A. [UNIFESP]; Lopes, Daiana S.; Rodrigues Avila, Veridiana de Melo; da Silva, Claudio V. (Frontiers Media Sa, 2017)
      Trypanosoma cruzi interacts with host cells, including cardiomyocytes, and induces the production of cytokines, chemokines, metalloproteinases, and glycan-binding proteins. Among the glycan-binding proteins is Galectin-3 ...

    • GerbB-2 expression is a better predictor for survival than galectin-3 or p53 in early-stage breast cancer 

      Logullo, Angela Flavia [UNIFESP]; Lopes, Andréa Braga de Godoy; Nonogaki, Suely; Soares, Fernando Augusto; Mourão Netto, Mario; Nishimoto, Inês Nobuko; Brentani, Maria Mitzi [UNIFESP] (Professor D A Spandidos, 2007-07-01)
      The definition of high risk patients with early stage breast cancer is still controversial. We evaluated the ability of galectin-3, c-erbB-2 and p53 immunohistochemical expression to predict recurrence and survival in a ...

    • Recruitment of galectin-3 during cell invasion and intracellular trafficking of Trypanosoma cruzi extracellular amastigotes 

      Machado, Fabricio Castro; Cruz, Lilian; Silva, Aline Alves da; Cruz, Mario Costa [UNIFESP]; Mortara, Renato Arruda [UNIFESP]; Roque-Barreira, Maria Cristina; Silva, Claudio Vieira da (Oxford Univ Press Inc, 2014-02-01)
      The invasion of host cells by the intracellular protozoan Trypanosoma cruzi requires interactions with host cell molecules, and the replication of the parasite requires escape from a parasitophorous vacuole into the host ...

    • A Role for galectin-3 in renal tissue damage triggered by ischemia and reperfusion injury 

      Fernandes Bertocchi, Ana Paula [UNIFESP]; Campanhole, Gabriela [UNIFESP]; Mei Wang, Pamella Huey [UNIFESP]; Goncalves, Giselle Martins [UNIFESP]; Damiao, Marcio Jose [UNIFESP]; Cenedeze, Marcos Antonio [UNIFESP]; Beraldo, Felipe Caetano; Antunes Teixeira, Vicente de Paula; Reis, Marlene Antonia dos; Mazzali, Marilda; Pacheco-Silva, Alvaro [UNIFESP]; Saraiva Camara, Niels Olsen [UNIFESP] (Wiley-Blackwell, 2008-10-01)
      Ischemic-reperfusion injury (IRI) triggers an inflammatory response involving neutrophils/macrophages, lymphocytes and endothelial cells. Galectin-3 is a multi-functional lectin with a broad range of action such as promotion ...