Browsing by Subject "fibril formation"

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Assessment of the Aggregation Propensity of the beta-amyloid Peptide During the Synthesis and when Free in Solution

Malavolta, Luciana [UNIFESP]; Pinto, Marcelo Rodrigo Silva [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP] (Bentham Science Publ Ltd, 2013-08-01)

This work developed an alternative approach targeting the evaluation of the aggregation propensity of the (1-42) beta-amyloid peptide (Alzheimer's disease) and some segments, either attached to a polymer during their ...
Evaluation of Aggregation and Fibril Formation Propensity of Peptides Involved in Amyloid Diseases

Malavolta, Luciana; Chinarelli, Ricardo Lobato; Sobral, Danielle Vieira; Nakaie, Clovis R. [UNIFESP] (Bentham Science Publ Ltd, 2017)

Background: Amyloidosis is defined as a generic term given to a series of proteins/polypeptides in the form of amyloid fibrils that are deposited in the tissues and give rise to a set of clinical disorders. Objectives: ...