Now showing items 1-10 of 30

    • Actin-rich structures formed during the invasion of cultured cells by infective forms of Trypanosoma cruzi 

      Procopio, Daniela de Oliveira [UNIFESP]; Barros, Helena Cristina [UNIFESP]; Mortara, Renato Arruda [UNIFESP] (Urban & Fischer Verlag, 1999-12-01)
      Previous work has shown that Trypanosoma cruzi extracellular amastigotes as well as metacyclic trypomastigotes infect cultured cells in a highly specific parasite form-cell type interaction. In this work we have investigated ...

    • Assembly of high molecular weight kininogen and activation of prekallikrein on cell matrix 

      Motta, G.; Shariat-Madar, Z.; Mahdi, F.; Sampaio, Claudio AM [UNIFESP]; Schmaier, A. H. (F K Schattauer Verlag Gmbh, 2001-09-01)
      Investigations determined if extracellular matrix of endothelial cells (EC) is a platform for HK assembly and PK activation. In buffers containing bovine serum albumin, biotin-RK binding to ECV304 cells or their matrix ...

    • Autoantibodies directed to extracellular matrix components in patients with different clinical forms of periodontitis 

      De-Gennaro, Luiz A.; Lopes, Jose D.; Mariano, Mario (Amer Acad Periodontology, 2006-12-01)
      Background: Periodontal disease occurs in different clinical forms, from mild and easily controllable to more aggressive inflammatory manifestations, with difficult clinical or surgical control. There is evidence that a ...

    • Cellular prion protein binds laminin and mediates neuritogenesis 

      Graner, E.; Mercadante, A. F.; Zanata, S. M.; Forlenza, O. V.; Cabral, ALB; Veiga, S. S.; Juliano, M. A.; Roesler, R.; Walz, R.; Minetti, A.; Izquierdo, I; Martins, V. R.; Brentani, R. R. (Elsevier B.V., 2000-03-10)
      Laminin (LN) plays a major role in neuronal differentiation, migration and survival. Here, we show that the cellular prion protein (PrPc) is a saturable, specific, high-affinity receptor for LN. the PrPc-LN interaction is ...

    • Cellular prion protein interaction with vitronectin supports axonal growth and is compensated by integrins 

      Hajj, Glaucia N. M.; Lopes, Marilene H.; Mercadante, Adriana F.; Veiga, Silvio Sanches [UNIFESP]; Silveira, Rafael Bertoni da [UNIFESP]; Santos, Tiago G.; Ribeiro, Karina C. B.; Juliano, Maria Aparecida [UNIFESP]; Jacchieri, Saul G.; Zanata, Silvio M.; Martins, Vilma R. (Company of Biologists Ltd, 2007-06-01)
      The physiological functions of the cellular prion protein, PrPC, as a cell surface pleiotropic receptor are under debate. We report that PrPC interacts with vitronectin but not with fibronectin or collagen. the binding ...

    • Concentração do ácido hialurônico em pregas vocais com edema de reinke 

      Melo, Cristiana Vanderlei de [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-11-29)
      Objective: The authors investigated the concentration of hyaluronic acid in Reinke's edema in the vocal fold cover. Method: For this study a hyaluronic acid binding protein isolated from bovine nasal cartilage was used. ...

    • Desordens matriciais da aorta em modelo knockout mg loxpneo na linhagem 129/sv da síndrome de marfan 

      Souza, Rodrigo Barbosa de [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-06-30)
      Marfan syndrome (MPS) is a dominant autosomal disease with gene mutations encoding fibrillin-1 protein, a constituent of elastic fibers systems widely distributed in the extracellular matrix, thus promoting skeletal ocular ...

    • Differential Gene Transcription of Extracellular Matrix Components in Response to In Vivo Corneal Crosslinking (CXL) in Rabbit Corneas 

      Kling, Sabine; Hammer, Arthur; Torres Netto, Emilio A. [UNIFESP]; Hafezi, Farhad (Assoc Research Vision Ophthalmology Inc, 2017)
      Purpose: We studied changes in gene transcription after corneal crosslinking (CXL) in the rabbit cornea in vivo and identified potential molecular signaling pathways. Methods: A total of 15 corneas of eight male New-Zealand-White ...

    • Efeitos imediato e tardio das isoflavonas da soja e do estradiol na glândula mamária de ratas ovariectomizadas 

      Santos, Miriam Aparecida dos [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2015-12-16)
      The importance of estrogen in the etiology of breast cancer is widely recognized. Studies indicate that women who have never received any kind of hormone therapy (HT) in menopause and who have to use it later, have an ...

    • The effect of brown spider venom on endothelial cell morphology and adhesive structures 

      Paludo, Katia Sabrina; Gremski, Luiza Helena; Veiga, Silvio Sanches; Chaim, Olga Meiri; Gremski, Waldemiro; Freitas Buchi, Dorly de; Nader, Helena Bonciani; Dietrich, Carl Peter; Franco, Celia Regina Cavichiolo [UNIFESP] (Elsevier B.V., 2006-06-15)
      Spiders of the Loxosceles genus have been responsible for severe clinical cases of envenomation worldwide. Accidents involving brown spiders can cause dermonecrotic injury, hemorrhage, hemolysis, platelet aggregation and ...