Now showing items 1-8 of 8

    • Blockade of Bradykinin Receptor B1 but Not Bradykinin Receptor B2 Provides Protection From Cerebral Infarction and Brain Edema 

      Austinat, Madeleine; Braeuninger, Stefan; Pesquero, João Bosco [UNIFESP]; Brede, Marc; Bader, Michael [UNIFESP]; Stoll, Guido; Renne, Thomas; Kleinschnitz, Christoph (Lippincott Williams & Wilkins, 2009-01-01)
      Background and Purpose-Brain edema is detrimental in ischemic stroke and its treatment options are limited. Kinins are proinflammatory peptides that are released during tissue injury. the effects of kinins are mediated by ...

    • The C-terminus of murine S100A9 inhibits hyperalgesia and edema induced by jararhagin 

      Dale, C. S.; Goncalves, LRC; Juliano, L.; Juliano, M. A.; Silva, AMM da; Giorgi, R. (Elsevier B.V., 2004-01-01)
      The effect of a synthetic peptide (H-92-G(110)) identical to the C-terminus of murine S100A9 (mS100A9p) was investigated on hyperalgesia and edema induced by either jararhagin or papain in the rat paw. mS100A9p not only ...

    • Cytotoxic, thrombolytic and edematogenic activities of leucurolysin-a, a metalloproteinase from Bothrops leucurus snake venom 

      Gremski, L. H.; Chaim, O. M.; Paludo, K. S.; Sade, Y. B.; Otuki, M. F.; Richardson, M.; Gremski, W.; Sanchez, E. F.; Veiga, S. S. (Elsevier B.V., 2007-07-01)
      Leucurolysin-a (leuc-a), a 23 kDa non-hemorrhagic metalloproteinase, is found in venom of the viper Bothrops leucurus. Here, we examine the biological consequences of leuc-a, including thrombolytic activity, direct effects ...

    • Fluid Redistribution in Sleep Apnea: Therapeutic Implications in Edematous States 

      da Silva, Bruno Caldin; Kasai, Takatoshi; Coelho, Fernando Morgadinho [UNIFESP]; Zatz, Roberto; Elias, Rosilene M. (Frontiers Media Sa, 2018)
      Sleep apnea (SA), a condition associated with increased cardiovascular risk, has been traditionally associated with obesity and aging. However, in patients with fluid-retaining states, such as congestive heart failure and ...

    • Isquemia retiniana e espessamento da coróide em pacientes diabéticos tipo 1 com microalbuminúria e sem alterações significativas ao exame de fundo de olho 

      Moura, Priscila Mariano de [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2015-12-31)
      To report findings and tomographic angiography of the retina and choroid of patients with diabetes mellitus (DM) type 1 with microalbuminuria and without significant changes to the examination of the fundus. METHODS: ...

    • Kininogenase activity of Thalassophryne nattereri fish venom 

      Lopes-Ferreira, M.; Emim, JADS; Oliveira, V; Puzer, L.; Cezari, M. H.; Araujo, MDS; Juliano, L.; Lapa, A. J.; Souccar, C.; Silva, AMMA (Elsevier B.V., 2004-12-01)
      Accidents caused by the venomous fish Thalassophryne nattereri are characterized by edema, intense pain and necrosis at the site of the sting. This study assessed the nociceptive and edematogenic activities of T nattereri ...

    • Mechanisms underlying the nociceptive and inflammatory responses induced by trypsin in the mouse paw 

      Paszcuk, Ana Flavia; Quintao, Nara L. M.; Fernandes, Elizabeth S.; Juliano, Luiz [UNIFESP]; Chapman, Kevin; Andrade-Gordon, Patricia; Campos, Maria Martha; Vergnolle, Nathalie; Calixto, Joao B. (Elsevier B.V., 2008-02-26)
      It has been demonstrated that trypsin is able to evoke the classical signals of inflammation, mainly via the activation of proteinase-activated receptor-2 (PAR-2). This study was designed to evaluate the inflammatory and ...

    • Meningeoma de goteira olfatória: relação entre achados clínico-radiológicos e índice proliferativo (Mib-1) 

      Paiva Neto, Manoel Antonio de [UNIFESP]; Tella Jr, Oswaldo Inácio de [UNIFESP]; Herculano, Marco Antonio [UNIFESP]; Stávale, João Norberto [UNIFESP]; Bonatteli, Antonio Pádua Furquim [UNIFESP] (Academia Brasileira de Neurologia - ABNEURO, 2006-03-01)
      OBJECTIVE: The aim of this study is to correlationate demografic, radiologic features and proliferative index defined by imunohistochemical expression of Mib-1 in olfactory groove meningiomas, and to observe possible ...