Now showing items 1-10 of 15

    • Cytokine Alterations in Bipolar Disorder: A Meta-Analysis of 30 Studies 

      Modabbernia, Amirhossein; Taslimi, Shervin; Brietzke, Elisa [UNIFESP]; Ashrafi, Mandana (Elsevier B.V., 2013-07-01)
      Background: We conducted a meta-analysis of studies comparing cytokine concentrations between patients with bipolar disorder (BD) and healthy control subjects (HCs).Methods: We searched ISI Web of Science, MEDLINE, BIOSIS ...

    • Effect of microcystin on leukocyte viability and function 

      Goncalves, EAP; Dalboni, Maria Aparecida [UNIFESP]; Peres, A. T.; Manfredi, A. P.; Manfredi, SR; Azevedo, S. M.; Magalhaes, V. F.; Draibe, S.; Canziani, MEF; Cendoroglo, M. (Elsevier B.V., 2006-06-01)
      Microcystin (MC) has been found in several areas of the world. in addition to its hepatotoxicity, microcystin may have an immunomodulatory effect.Considering that patients receiving hemodialysis may be chronically exposed ...

    • Evaluating budesonide efficacy in nasal polyposis and predicting the resistance to treatment 

      Valera, F. C. P.; Queiroz, R.; Scrideli, C.; Tone, L. G.; Anselmo-Lima, W. T. (Wiley-Blackwell, 2009-01-01)
      Cell resistance to glucocorticoids is a major problem in the treatment of nasal polyposis (NP).The objectives of this study were to observe the effect of budesonide on the expression of IL-1 beta, TNF-alpha, granulocyte ...

    • Evidence for Involvement of IL-9 and IL-22 in Cows' Milk Allergy in Infants 

      Barros, Karina V. [UNIFESP]; Flor Silveira, Vera L. [UNIFESP; Laranjeira, Marisa S.; Wandalsen, Neusa F.; Passeti, Susana; De Oliveira, Roberta; Munekata, Regina V.; Noakes, Paul S.; Miles, Elizabeth A.; Calder, Philip C. (Mdpi Ag, 2017)
      Although allergic inflammation is characterized by a T helper (Th) 2-dominant immune response, the discovery of a role for new T cell subsets in inflammatory diseases has added an additional layer of complexity to the ...

    • Genetic Polymorphisms and Recurrent Spontaneous Abortions: An Overview of Current Knowledge 

      Daher, Silvia [UNIFESP]; Mattar, Rosiane [UNIFESP]; Gueuvoghlanian-Silva, Barbara Y. [UNIFESP]; Torloni, Maria R. [UNIFESP] (Wiley-Blackwell, 2012-04-01)
      The relevance of gene polymorphisms in the development of unexplained recurrent spontaneous abortion is still unclear. Cytokines, angiogenic mediators, and hormones are involved in all stages of reproduction and pregnancy ...

    • Histoplasma capsulatum-Induced Cytokine Secretion in Lung Epithelial Cells Is Dependent on Host Integrins, Src-Family Kinase Activation, and Membrane Raft Recruitment 

      Maza, Paloma Korehisa [UNIFESP]; Suzuki, Erika [UNIFESP] (Frontiers Media Sa, 2016)
      Histoplasma capsulatum var. capsulatum is a dimorphic fungus that causes histoplasmosis, a human systemic mycosis with worldwide distribution. In the present work, we demonstrate that H. capsulatum yeasts are able to induce ...

    • Hypogammaglobulinemia in children: a warning sign to look deeply? 

      de Melo, Karina Mescouto [UNIFESP]; de Moraes-Pinto, Maria Isabel [UNIFESP]; Andrade, Luis E. C. [UNIFESP]; Salomao, Reinaldo [UNIFESP]; Brunialti, Milena K. C. [UNIFESP]; Ferreira, Vanessa S. [UNIFESP]; Costa-Carvalho, Beatriz T. [UNIFESP] (Wiley, 2017)
      This study investigated phenotypic and functional characteristics of lymphocytes in children with common variable immunodeficiency (CVID) and unclassified hypogammaglobulinemia (UH), as well as B-cell subsets in ...

    • IL-12 inhibits endotoxin-induced inflammation in the eye 

      Whitcup, S. M.; Rizzo, L. V.; Lai, J. C.; Hayashi, S.; Gazzinelli, R.; Chan, C. C. (Vch Publishers Inc, 1996-05-01)
      Interleukin-12 (IL-12) is a heterodimeric cytokine that induces interferon (IFN)-gamma production and an increased generation of Th 1 cells. Both IL-12 and IL-12 antagonists are being studied for the treatment of allergic ...

    • Impaired Treg and NK cells profile in overweight women with gestational diabetes mellitus 

      Lobo, Thalita Frutuoso [UNIFESP]; Borges, Cannila de Moraes [UNIFESP]; Mattar, Rosiane [UNIFESP]; Gomes, Caio Perez [UNIFESP]; Angelo, Ana Geisa Santos de [UNIFESP]; Pendeloski, Karen Priscilla Tezotto [UNIFESP]; Daher, Silvia [UNIFESP] (Wiley, 2018)
      Problem: Maternal obesity is frequently associated with gestational diabetes mellitus (GDM), and immunological mechanisms seem to be involved in the physiopathology of these conditions. The aim of this study was to ...

    • Maternal obesity and inflammatory mediators: A controversial association 

      Pendeloski, Karen Priscilla Tezotto [UNIFESP]; Ono, Erika [UNIFESP]; Torloni, Maria ReginaV; Mattar, RosianeV [UNIFESP]; Daher, Silvia [UNIFESP] (Wiley, 2017)
      The link between maternal obesity and inflammatory mediators is still unclear. Our aim was to summarize the main findings of recently published studies on this topic. We performed a search in Medline for studies published ...