Browsing by Subject "cancer"

Now showing items 1-10 of 46

    • Anti-tumor effect of endostatin mediated by retroviral gene transfer in mice bearing renal cell carcinoma 

      Coutinho, Enia Lucia [UNIFESP]; Andrade, Luciana Nogueira de Sousa; Chammas, Roger; Morganti, Ligia; Schor, Nestor [UNIFESP]; Bellini, Maria Helena [UNIFESP] (Federation Amer Soc Exp Biol, 2007-10-01)
      We investigated whether transfer of the gene encoding the angiogenesis inhibitor endostatin into the NIH/3T3 fibroblast cell line could inhibit renal tumor growth in vivo. NIH/3T3 cells were transduced with retroviral ...

    • Apoptotic effects of inositol hexaphosphate on biomarker Itpr3 in induced colon rat carcinogenesis 

      Marks, Guido [UNIFESP]; Fagundes, Djalma José [UNIFESP]; Ynouye, Celso Massaschi; Pontes, Elenir Rose Jardim Cury; Takita, Luiz Carlos [UNIFESP]; Amaral, Eva Glória Abrão Siufi do [UNIFESP]; Teruya, Roberto [UNIFESP]; Paes, Manoel Catarino; Brasileiro, José Lacerda [UNIFESP]; Aydos, Ricardo Dutra [UNIFESP] (Acta Cirurgica Brasileira, 2008-03-01)
      Purpose: To study the effect of the modulation of inositol hexaphosphate (IP6) in the biological immunohistochemistry expression of cellular signaling marker apoptosis, in model of carcinogenesis of colon induced by ...

    • Avaliação da atividade proliferativa do epitélio mamário de mulheres após a utilização de três ciclos anticoncepcional hormonal com combinado oral 

      Fenile, Rogerio [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-03-31)
      The most controversial aspect in relation to oral hormonal contraception is the risk of developing breast cancer. Knowledge of the factors that influence the proliferation of normal breast epithelium is essential to ...

    • Avaliação do efeito analgésico da associação de magnésio com morfina na dor de pacientes com câncer: estudo clínico randomizado duplo-cego 

      Baaklini, Luis Gustavo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2015-07-31)
      Objectives: The aim of this study was to evaluate if the association of Mg enhances the analgesic effect of morphine in cancer pain. Methods: The study was prospective, randomized, double-blinded, and comparative with ...

    • Bcl-2 oncogene expression in estrogen receptor-positive and negative breast carcinoma 

      Santos, L. G. dos; Lopes-Costa, P. V.; Santos, A. R. dos; Facina, Gil [UNIFESP]; Silva, B. B. da (I R O G Canada, Inc, 2008-01-01)
      Purpose: The aim of this study was to evaluate Bcl-2 oncogene expression in estrogen receptor (ER)-positive and negative breast carcinomas. Methods: A Study involving 72 cases of infiltrating ductal carcinoma of the breast ...

    • Blocking the Proliferation of Human Tumor Cell Lines by Peptidase Inhibitors from Bauhinia Seeds 

      Nakahata, Adriana Miti [UNIFESP]; Mayer, Barbara; Neth, Peter; Hansen, Daiane [UNIFESP]; Sampaio, Misako Uemura [UNIFESP]; Oliva, Maria Luiza Vilela [UNIFESP] (Georg Thieme Verlag Kg, 2013-03-01)
      In cancer tumors, growth, invasion, and formation of metastasis at a secondary site play a pivotal role, participating in diverse processes in the development of the pathology, such as degradation of extracellular matrix. ...

    • Breast and gynecological cancer patients' risk factors associated with biopsychosocial problem-related distress 

      Bergerot, Cristiane Decat [UNIFESP]; Clark, Karen Lynn; Obenchain, Richard; Philip, Errol J.; Loscalzo, Matthew (Wiley, 2018)
      Objectives: Inequalities exist between breast and gynecological cancer patients' experiences, leading to high levels of distress throughout the cancer journey. The present study aims to identify differences in source of ...

    • Caesalpinioflavone, a New Cytotoxic Biflavonoid Isolated from Caesalpinia pluviosa var. peltophoroides 

      Zanin, Joao L. B.; Massoni, Murilo; Santos, Marcelo H. dos; Freitas, Giovana C. de; Niero, Evandro L. O.; Schefer, Renata R.; Lago, Joao H. G. [UNIFESP]; Ionta, Marisa; Soares, Marisi G. (Soc Brasileira Quimica, 2015-04-01)
      The present study aimed to investigate the presence of compounds with antitumor activity in the plant Caesalpinia pluviosa var. peltophoroides. From bioactivity guided studies it was possible to isolate a new biflavonoid, ...

    • Cancer stem cell genomics: the quest for early markers of malignant progression 

      Okamoto, Oswaldo Keith [UNIFESP] (Expert Reviews, 2009-09-01)
      Biologically distinct populations of neoplastic stem cells have been identified in a variety of human cancers, in which they are associated with the initial steps of tumorigenesis. the intrinsic properties of self-renewal, ...

    • Centromeres in cell division, evolution, nuclear organization and disease 

      Santos Silva, Amanda Goncalves dos [UNIFESP]; Sarkar, Rahul; Harizanova, Jana; Guffei, Amanda; Mowat, Michael; Garini, Yuval; Mai, Sabine (Wiley-Blackwell, 2008-08-15)
      As the spindle fiber attachment region of the chromosome, the centromere has been investigated in a variety of contexts. Here, we will review current knowledge about this unique chromosomal region and its relevance for ...