Browsing by Subject "calcium"

Now showing items 1-10 of 39

    • Absence of suppressor of cytokine signaling 2 turns cardiomyocytes unresponsive to LIF-dependent increases in Ca2+ levels 

      Rocha-Resende, Cibele; Guedes de Jesus, Itamar Couto; Roman-Campos, Danilo [UNIFESP]; Miranda, Artur S.; Alves, Fabiana; Resende, Rodrigo Ribeiro; Cruz, Jader dos Santos; Machado, Fabiana Simao; Guatimosim, Silvia (Amer Physiological Soc, 2017)
      Little is known regarding the role of suppressor of cytokine signaling (SOCS) in the control of cytokine signaling in cardiomyocytes. We investigated the consequences of SOCS2 ablation for leukemia inhibitory factor ...

    • Angiotensin II Binding to Angiotensin I-Converting Enzyme Triggers Calcium Signaling 

      Guimarães, Paola Bianchi [UNIFESP]; Alvarenga, Erika Costa [UNIFESP]; Siqueira, Paula D. [UNIFESP]; Paredes-Gamero, Edgar Julian [UNIFESP]; Sabatini, Regiane Angelica [UNIFESP]; Morais, Rafael Leite Tavares de [UNIFESP]; Reis, Rosana I.; Santos, Edson L.; Teixeira, Luis Gustavo de Deus [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Martin, Renan Paulo [UNIFESP]; Shimuta, Suma Imura [UNIFESP]; Carmona, Adriana Karaoglanovic [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP]; Jasiulionis, Miriam Galvonas [UNIFESP]; Ferreira, Alice Teixeira [UNIFESP]; Pesquero, Jorge L.; Oliveira, Suzana M. [UNIFESP]; Bader, Michael [UNIFESP]; Costa-Neto, Claudio M.; Pesquero, João Bosco [UNIFESP] (Lippincott Williams & Wilkins, 2011-05-01)
      Angiotensin (Ang) I-converting enzyme (ACE) is involved in the control of blood pressure by catalyzing the conversion of Ang I into the vasoconstrictor Ang II and degrading the vasodilator peptide bradykinin. Human ACE ...

    • Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes 

      Hirata, H.; Machado, L. S.; Okuno, C. S.; Brasolin, A.; Lopes, G. S.; Smaili, Soraya Soubhi [UNIFESP] (Elsevier B.V., 2006-01-30)
      In this study, we investigated agents that increased intracellular calcium levels and their correlation with apoptotic cell death induction. We used rat astrocytes to investigate the increase in cytosolic Ca2+, (Ca-c(2+)) ...

    • Calcium and cell death signaling in neurodegeneration and aging 

      Smaili, Soraya Soubhi [UNIFESP]; Hirata, Hanako [UNIFESP]; Ureshino, Rodrigo Portes [UNIFESP]; Monteforte, Priscila T. [UNIFESP]; Morales, Ana P. [UNIFESP]; Muler, Mari Luminosa [UNIFESP]; Terashima, Juliana [UNIFESP]; Oseki, Karen Tubono [UNIFESP]; Rosenstock, Tatiana R. [UNIFESP]; Lopes, Guiomar Silva [UNIFESP]; Bincoletto, Claudia [UNIFESP] (Academia Brasileira de Ciências, 2009-09-01)
      Transient increase in cytosolic (Cac2+) and mitochondrial Ca2+ (Ca m2+) are essential elements in the control of many physiological processes. However, sustained increases in Ca c2+ and Ca m2+ may contribute to oxidative ...

    • Calcium and magnesium concentrations in mature human milk: influence of calcium intake, age and socioeconomic level 

      Vitolo, Marcia Regina [UNIFESP]; Soares, LM Valente; Carvalho, E. B.; Cardoso, C. B. (Archivos Latinoamericanos Nutricion, 2004-03-01)
      Concentrations of calcium and magnesium were measured in mature milk, collected between 30 and 90 days after childbirth, from a group of 90 mothers between 14 and 39 years of age, exclusively breastfeeding. The group was ...

    • Calcium intake and its relationship with adiposity and insulin resistance in post-pubertal adolescents 

      Santos, L. C. dos; Cintra, I. de Padua [UNIFESP]; Fisberg, M. [UNIFESP]; Martini, L. A. (Wiley-Blackwell, 2008-04-01)
      Background Dietary calcium intake has been described as being a negative contributor to adiposity. in adolescents, this relationship is not well established. the objectives of the present study were to compare the calcium ...

    • Calcium modulates endopeptidase 24.15 (EC 3.4.24.15) membrane association, secondary structure and substrate specificity 

      Oliveira, Vitor; Garrido, Paula AG; Rodrigues, Claudia C.; Colquhoun, Alison; Castro, Leandro M.; Almeida, Paulo C.; Shida, Claudio S.; Juliano, Maria Aparecida [UNIFESP]; Juliano, Luiz [UNIFESP]; Camargo, Antonio CM; Hyslop, Stephen; Roberts, James L.; Grum-Tokars, Valerie; Glucksman, Marc J.; Ferro, Emer S. (Blackwell Publishing, 2005-06-01)
      The metalloendopeptidase 24.15 (EP24.15) is ubiquitously present in the extracellular environment as a secreted protein. Outside the cell, this enzyme degrades several neuropeptides containing from 5 to 17 amino acids (e.g. ...

    • Cálcio dietético: estratégias para otimizar o consumo 

      Pereira, Giselle A. P. [UNIFESP]; Genaro, Patrícia S.; Pinheiro, Marcelo de Medeiros [UNIFESP]; Szejnfeld, Vera Lucia [UNIFESP]; Martini, Lígia A. (Sociedade Brasileira de Reumatologia, 2009-04-01)
      Calcium is an essential nutrient required for numerous biological functions. Studies have demonstrated an association between low calcium intake and chronic diseases, such as osteoporosis, colon cancer, hypertension, and ...

    • Cell-Permeable Gomesin Peptide Promotes Cell Death by Intracellular Ca2+ Overload 

      Paredes-Gamero, Edgar J. [UNIFESP]; Casaes-Rodrigues, Rafael L. [UNIFESP]; Moura, Gioconda E. D. D. [UNIFESP]; Domingues, Tatiana Moreira [UNIFESP]; Buri, Marcus V. [UNIFESP]; Ferreira, Victor H. C.; Trindade, Edvaldo S.; Moreno-Ortega, Ana J.; Cano-Abad, Maria F.; Nader, Helena B. [UNIFESP]; Ferreira, Alice T. [UNIFESP]; Miranda, Antonio [UNIFESP]; Justo, Giselle Z. [UNIFESP]; Tersariol, Ivarne L. S. [UNIFESP] (Amer Chemical Soc, 2012-09-01)
      In recent years, the antitumoral activity of antimicrobial peptides (AMPs) has been the goal of many research studies. Among AMPs, gomesin (Gm) displays antitumor activity by unknown mechanisms. Herein, we studied the ...

    • Comparison between two methods of ionized calcium measurement in newborns 

      Basseto, Thaís P.; Azzalis, Ligia Ajaime [UNIFESP]; Pereira, Edimar Cristiano [UNIFESP]; Junqueira, Virginia Berlanga Campos [UNIFESP]; Caputo, Luciana Zambelli; Fonseca, Alexandre Luiz Affonso; Feder, David; Fonseca, Fernando Luiz Affonso [UNIFESP] (Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, 2013-10-01)
      Changes in ionized calcium (iCa) concentration seem to occur in newborns when the calcium supply from the mother is disconnected at birth, and a related hypocalcemia is produced. Thus, measurement of iCa is of particular ...