Now showing items 1-7 of 7

    • Análise do tempo de sobrevida de doentes com adenocarcinoma colorretal esporádico pela utilização de um painel de biomarcadores de carcinogênese constituído por vegf, egfr, ki-67, p53 e bcl-2 

      Luderer, Loreley Andrade [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014-12-17)
      Objective: To evaluate the prognostic power of survival of a carcinogenesis biomarkers panel formed by p53, VEGF, Bcl-2, Ki-67, and EGFR in subjects with sporadic colorectal adenocarcinoma subjected to radical surgical ...

    • Bcl-2 oncogene expression in estrogen receptor-positive and negative breast carcinoma 

      Santos, L. G. dos; Lopes-Costa, P. V.; Santos, A. R. dos; Facina, Gil [UNIFESP]; Silva, B. B. da (I R O G Canada, Inc, 2008-01-01)
      Purpose: The aim of this study was to evaluate Bcl-2 oncogene expression in estrogen receptor (ER)-positive and negative breast carcinomas. Methods: A Study involving 72 cases of infiltrating ductal carcinoma of the breast ...

    • Cell-Cycle Analysis and Apoptosis-associated Proteins in Cervical Lesions of Brazilian Women 

      Dobo, Cristine [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Lima, Flavio de Oliveira [UNIFESP]; Gomes, Thiago Simao [UNIFESP]; Stavale, Joao Norberto [UNIFESP]; Arias, Vitor [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Focchi, Gustavo Rubino de Azevedo [UNIFESP] (Int Inst Anticancer Research, 2014-06-01)
      Aim: The aim of the present study was to detect the relative expressions of p53, p21(Waf1/Cip1), p27(Kip1) Bcl-2 and cleaved caspase-3 in cervical lesion samples from Brazilian women by immunohistochemistry. Materials and ...

    • Comparison of positivity frequency of bcl-2 expression in prostate adenocarcinoma with low and high Gleason score 

      Hering, Flavio Luis Ortiz [UNIFESP]; Lipay, Mônica Vannucci Nunes [UNIFESP]; Lipay, Marco Aurélio Silva [UNIFESP]; Rodrigues, Paulo Roberto Teixeira [UNIFESP]; Nesralah, Luciano José [UNIFESP]; Srougi, Miguel [UNIFESP] (Associação Paulista de Medicina - APM, 2001-07-01)
      CONTEXT: Multiple genetic and epigenetic factors have been implicated in the oncogenesis and progression of prostate cancer. The major difficulty is in that the clinical management stems from the reality that reliable and ...

    • Gemistocytes in astrocytomas: Are they a significant prognostic factor? 

      Martins, Dely C.; Malheiros, Suzana M.; Santiago, Lucila H.; Stavale, Joao N. (Springer, 2006-10-01)
      Our aim was to retrospectively evaluate the influence of gemistocytic astrocytes, cellular proliferation indices, immunoexpression of proteins p53 and bcl-2 in the clinical outcome of 39 patients with WHO grade II and III ...

    • Increase in bax expression and apoptosis are associated in Huntington's disease progression 

      Teles, A. V. F. F. [UNIFESP]; Rosenstock, T. R. [UNIFESP]; Okuno, C. S. [UNIFESP]; Lopes, G. S. [UNIFESP]; Bertoncini, C. R. A. [UNIFESP]; Smaili, Soraya Soubhi [UNIFESP] (Elsevier B.V., 2008-06-13)
      Huntington's disease (HD) is a hereditary dominant neurodegenerative disorder and the progression of the disease may be associated with apoptosis and altered expression of apoptotic proteins. the aim of this study was to ...

    • Sleep deprivation does not affect indices of necrosis or apoptosis in rat brain 

      Hipólide, Débora Cristina [UNIFESP]; D'Almeida, Vania [UNIFESP]; Raymond, Roger; Tufik, Sergio [UNIFESP]; Nobrega, J. N. (Taylor & Francis Ltd, 2002-02-01)
      Recent indications of oxidative stress in hypothalamus of sleep deprived rats prompted us to address the possibility that sleep deprivation may induce pathological cell loss changes in brain. Indices of necrosis and apoptosis ...