Now showing items 1-4 of 4

    • Distinct effects of sleep deprivation on binding to norepinephrine and serotonin transporters in rat brain 

      Hipolide, Debora C. [UNIFESP]; Moreira, Karin M. [UNIFESP]; Barlow, KBL; Wilson, A. A.; Nobrega, J. N.; Tufik, Sergio [UNIFESP] (Elsevier B.V., 2005-02-01)
      There is evidence to suggest that the antidepressant activity of sleep deprivation may be due to an enhancement of serotonergic and/or noradrenergic neurotransmission in brain. in the present study we examined the possibility ...

    • Heightened aggression after chronic flunitrazepam in male rats: potential links to cortical and caudate-putamen-binding sites 

      Almeida, Rosa Maria M. de; Benini, Quelin; Betat, Juliana S.; Hipolide, Debora C. [UNIFESP]; Miczek, Klaus A.; Svensson, Anders I. (Springer, 2008-04-01)
      Rationale Higher doses of benzodiazepines induce sedation. However, in low to moderate doses, benzodiazepines can increase aggressive behavior both after acute and chronic administration. the determinants for increasing ...

    • Morphine attenuates the expression of sensitization to ethanol, but opioid antagonists do not 

      Abrahao, Karina Possa [UNIFESP]; Quadros, I. M.; Souza-Formigoni, M. L. O. [UNIFESP] (Elsevier B.V., 2008-10-28)
      Behavioral sensitization to ethanol is characterized by an increased locomotor activity after repeated exposure. A great variability exists among species and strains in the development of sensitization. There is a growing ...

    • Sleep deprivation does not affect indices of necrosis or apoptosis in rat brain 

      Hipólide, Débora Cristina [UNIFESP]; D'Almeida, Vania [UNIFESP]; Raymond, Roger; Tufik, Sergio [UNIFESP]; Nobrega, J. N. (Taylor & Francis Ltd, 2002-02-01)
      Recent indications of oxidative stress in hypothalamus of sleep deprived rats prompted us to address the possibility that sleep deprivation may induce pathological cell loss changes in brain. Indices of necrosis and apoptosis ...