Browsing by Subject "antiretroviral therapy"
Now showing items 1-10 of 12
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Comparative studies of two-times-daily versus three-times-daily indinavir in combination with zidovudine and lamivudine
(Lippincott Williams & Wilkins, 2000-09-08)Objectives: To compare the efficacy and safety of two-times-daily versus three-times-daily indinavir in combination with zidovudine and lamivudine. Design: Two multicenter, open-label, randomized 24-week studies.Methods: ...
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Effect of GB virus C on response to antiretroviral therapy in HIV-infected Brazilians
(Blackwell Publishing, 2006-01-01)ObjectivesGB virus C (GBV-C) infection is associated with delayed mortality in HIV-infected people in most, but not all, studies. Previous investigations of the effect of GBV-C viraemia on response to antiretroviral therapy ...
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Evaluation of HIV-1 resistance to antiretroviral drugs among 150 patients after six months of therapeutic interruption
(Royal Soc Medicine Press Ltd, 2012-02-01)Most of the antiretroviral (ARV) studies in Brazil have been reported in treatment-experienced and naive patients rather than in the setting of treatment interruption (TI). in this study, we analysed reasons given for TI ...
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HIV-1 drug resistance genotypic profiles in children with undetectable plasma viremia during antiretroviral therapy
(Brazilian Society of Infectious Diseases, 2011-02-01)Treatment of HIV-1 infection with highly active antiretroviral therapy has led to sustained viral suppression in the plasma in a large number of children. However, studies have suggested that the integrated provirus in ...
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HIV-1 viremia during the first 28 weeks of pregnancy is not associated with mother-to-child transmission
(Brazilian Society of Infectious Diseases, 2006-08-01)It is currently recommended that antiretroviral prophylaxis to prevent mother-to-child transmission (MTCT) of HIV be initiated at 14 weeks of gestation. However, the relevance of early-gestation HIV viral load level for ...
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HIV-1-Infected children on HAART: Immunologic features of three different levels of viral suppression
(Wiley-Blackwell, 2007-01-15)Background: HIV-1-infected children show changes of blood lymphocyte subpopulations. We have, therefore, investigated how highly active anti-retroviral therapy (ART) alter these subsets. Blood samples were taken from 41 ...
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The impact of facial lipoatrophy treatment with polymethyl methacrylate in AIDS patients as measured by four quality-of-life questionnaires
(Royal Soc Medicine Press Ltd, 2011-10-01)Life-expectancy increased in patients infected with HIV/AIDS with the advent of highly active antiretroviral therapy (ART). Facial lipoatrophy is a common complication in these patients, eventually leading to stigma, ...
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Insulin Resistance and Glucose and Lipid Concentrations in a Cohort of Perinatally HIV-infected Latin American Children
(Lippincott Williams & Wilkins, 2013-07-01)We measured glucose, insulin and lipids in 249 perinatally HIV-infected Latin American children. Only 1 subject had impaired fasting glucose; 6.8% had insulin resistance. Abnormalities in total, low-density lipoprotein and ...
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Interaction between pediatric HIV infection and measles
(Future Medicine Ltd, 2011-12-01)Infections by measles virus and by HIV cause a state of immunodeficiency in the host. While measles virus leads to a transient immunodeficiency with depression of cellular mediated immunity, natural HIV infection leads to ...
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The management of HIV-infected pregnant women
(Lippincott Williams & Wilkins, 2012-12-01)Purpose of reviewThe purpose of this article is to update the current practice in the management of HIV-infected pregnant women and present evidence-based recommendations for the reduction of mother-to-child transmission.Recent ...