Browsing by Subject "angiotensin I-converting enzyme"

Now showing items 1-10 of 11

    • Angiotensin converting enzymes from human urine of mild hypertensive untreated patients resemble the N-terminal fragment of human angiotensin I-converting enzyme 

      Casarini, D. E.; Plavinik, F. L.; Zanella, M. T.; Marson, O.; Krieger, J. E.; Hirata, I. Y.; Stella, RCR (Elsevier B.V., 2001-01-01)
      Angiotensin I-converting enzyme (ACE) activity was analyzed in human urine collected from mild hypertensive untreated patients. DEAE-cellulose chromatography using linear gradient elution revealed two forms of angiotensin ...

    • Angiotensin converting-like enzymes from urine of untreated renovascular hypertensive and normal patients: purification and characterization 

      Costa, R. H.; Casarini, D. E.; Plavnik, F. L.; Marson, O.; Alves, K. B. (Elsevier B.V., 2000-03-01)
      Angiotensin converting-like enzymes (ACE) were isolated from urine of normal (P0N, P1N and P2N) and untreated renovascular hypertensive (P-0, P-1 and P-2) patients, the urine were submitted to ion exchange chromatography. ...

    • Angiotensin II Binding to Angiotensin I-Converting Enzyme Triggers Calcium Signaling 

      Guimarães, Paola Bianchi [UNIFESP]; Alvarenga, Erika Costa [UNIFESP]; Siqueira, Paula D. [UNIFESP]; Paredes-Gamero, Edgar Julian [UNIFESP]; Sabatini, Regiane Angelica [UNIFESP]; Morais, Rafael Leite Tavares de [UNIFESP]; Reis, Rosana I.; Santos, Edson L.; Teixeira, Luis Gustavo de Deus [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Martin, Renan Paulo [UNIFESP]; Shimuta, Suma Imura [UNIFESP]; Carmona, Adriana Karaoglanovic [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP]; Jasiulionis, Miriam Galvonas [UNIFESP]; Ferreira, Alice Teixeira [UNIFESP]; Pesquero, Jorge L.; Oliveira, Suzana M. [UNIFESP]; Bader, Michael [UNIFESP]; Costa-Neto, Claudio M.; Pesquero, João Bosco [UNIFESP] (Lippincott Williams & Wilkins, 2011-05-01)
      Angiotensin (Ang) I-converting enzyme (ACE) is involved in the control of blood pressure by catalyzing the conversion of Ang I into the vasoconstrictor Ang II and degrading the vasodilator peptide bradykinin. Human ACE ...

    • Carbamazepine inhibits angiotensin I-converting enzyme, linking it to the pathogenesis of temporal lobe epilepsy 

      Almeida, S. S. [UNIFESP]; Naffah-Mazzacoratti, Maria da Graca [UNIFESP]; Guimarães, Paola Bianchi [UNIFESP]; Wasinski, F. [UNIFESP]; Pereira, F. E. G. [UNIFESP]; Canzian, Mauro [UNIFESP]; Centeno, Ricardo Silva [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP]; Carmona, Adriana Karaoglanovic [UNIFESP]; Vieira, Renata de Freitas Fisher [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP]; Sabatini, R. A. [UNIFESP]; Perosa, S. R. [UNIFESP]; Bacurau, Reury Frank Pereira; Gouveia, Telma Luciana Furtado [UNIFESP]; Gallo, Gloria [UNIFESP]; Wuertele, M. [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP]; Silva, J. A.; Pesquero, João Bosco [UNIFESP]; Araujo, R. C. [UNIFESP] (Nature Publishing Group, 2012-03-01)
      We find that a common mutation that increases angiotensin I-converting enzyme activity occurs with higher frequency in male patients suffering from refractory temporal lobe epilepsy. However, in their brains, the activity ...

    • Catalytic properties of recombinant dipeptidyl carboxypeptidase from Escherichia coli: a comparative study with angiotensin I-converting enzyme 

      Cunha, Carlos Eduardo L. [UNIFESP]; Magliarelli, Helena de Fatima [UNIFESP]; Paschoalin, Thaysa [UNIFESP]; Nchinda, Aloysius T.; Lima, Jackson C. [UNIFESP]; Juliano, Maria A. [UNIFESP]; Paiva, Paulo B. [UNIFESP]; Sturrock, Edward D.; Travassos, Luiz R. [UNIFESP]; Carmona, Adriana K. [UNIFESP] (Walter de Gruyter & Co, 2009-09-01)
      Dipeptidyl carboxypeptidase from Escherichia coli (EcDcp) is a zinc metallopeptidase with catalytic properties closely resembling those of angiotensin I-converting enzyme (ACE). However, EcDcp and ACE are classified in ...

    • Characterization of angiotensin I-converting enzyme N-domain selectivity using positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides 

      Bersanetti, Patricia A. [UNIFESP]; Sabatini, Regiane A. [UNIFESP]; Matos, Beatriz S. [UNIFESP]; Douglas, Ross G.; Nchinda, Aloysius; Juliano, Maria A. [UNIFESP]; Pesquero, Joao Bosco [UNIFESP]; Sturrock, Edward D.; Carmona, Adriana K. [UNIFESP] (Walter de Gruyter & Co, 2012-12-01)
      Somatic angiotensin I-converting enzyme (ACE) has two homologous active sites (N and C domains) that show differences in various biochemical properties. in a previous study, we described the use of positional-scanning ...

    • Determination of angiotensin I-converting enzyme activity in cell culture using fluorescence resonance energy transfer peptides 

      Sabatini, R. A.; Bersanetti, P. A.; Farias, S. L.; Juliano, L.; Juliano, M. A.; Casarini, D. E.; Carmona, A. K.; Paiva, A. C. M.; Pesquero, J. B. (Elsevier B.V., 2007-04-15)
      An assay using fluorescence resonance energy transfer peptides was developed to assess angiotensin I-converting enzyme (ACE) activity directly on the membrane of transfected Chinese hamster ovary cells (CHO) stably expressing ...

    • Expression of angiotensin I-converting enzymes and bradykinin B-2 receptors in mouse inner medullary-collecting duct cells 

      Redublo Quinto, Beata Marie [UNIFESP]; Camargo de Andrade, Maria Claudina [UNIFESP]; Ronchi, Fernanda Aparecida [UNIFESP]; Santos, Edson Lucas; Corrêa, Silvana Aparecida Alves [UNIFESP]; Shimuta, Suma Imura; Pesquero, Joao Bosco; Mortara, Renato Arruda; Casarini, Dulce Elena [UNIFESP] (Elsevier B.V., 2008-02-01)
      We described in mouse inner medullary-collecting duct cells (m1MCD-3) the somatic and the N-domain ACE synthesis and its interaction with the kallikrein-kinin system co-localized in the same cells. We purified two ACE forms ...

    • Internally quenched fluorogenic substrates for angiotensin I-converting enzyme 

      Araujo, M. C.; Melo, R. I.; Del Nery, E.; Alves, MFM; Juliano, M. A.; Casarini, D. E.; Juliano, T.; Carmona, A. K. (Lippincott Williams & Wilkins, 1999-05-01)
      Objective Development of internally quenched fluorogenic substrates for sensitive and continuous assays of angiotensin I-converting enzyme (ACE).Design We synthesized internally quenched fluorogenic bradykinin-related ...

    • N-domain angiotensin-converting enzyme isoform expression in tissues of Wistar and spontaneously hypertensive rats 

      Ronchi, F. A.; Andrade, MCC; Carmona, A. K.; Krieger, J. E.; Casarini, D. E. (Lippincott Williams & Wilkins, 2005-10-01)
      Background Angiotensin I-converting enzyme (ACE) is a protein containing two active sites, called N- and C-domains, according to their position in the protein.Aim the aim of the present study was to verify whether the ...