Now showing items 1-10 of 19

    • Angiotensin II Binding to Angiotensin I-Converting Enzyme Triggers Calcium Signaling 

      Guimarães, Paola Bianchi [UNIFESP]; Alvarenga, Erika Costa [UNIFESP]; Siqueira, Paula D. [UNIFESP]; Paredes-Gamero, Edgar Julian [UNIFESP]; Sabatini, Regiane Angelica [UNIFESP]; Morais, Rafael Leite Tavares de [UNIFESP]; Reis, Rosana I.; Santos, Edson L.; Teixeira, Luis Gustavo de Deus [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Martin, Renan Paulo [UNIFESP]; Shimuta, Suma Imura [UNIFESP]; Carmona, Adriana Karaoglanovic [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP]; Jasiulionis, Miriam Galvonas [UNIFESP]; Ferreira, Alice Teixeira [UNIFESP]; Pesquero, Jorge L.; Oliveira, Suzana M. [UNIFESP]; Bader, Michael [UNIFESP]; Costa-Neto, Claudio M.; Pesquero, João Bosco [UNIFESP] (Lippincott Williams & Wilkins, 2011-05-01)
      Angiotensin (Ang) I-converting enzyme (ACE) is involved in the control of blood pressure by catalyzing the conversion of Ang I into the vasoconstrictor Ang II and degrading the vasodilator peptide bradykinin. Human ACE ...

    • Caracterização do sistema renina angiotensina no rim e coração do camundongo transgênico que expressa tonina de rato 

      Ribeiro, Amanda Aparecida [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-05-26)
      Angiotensin II (Ang II), one of the most relevant angiotensinergic peptides, has an important role in the renal and cardiac physiology. There are many enzymes that generate Ang II. One of them is tonin, that is able to ...

    • Differential sympathetic and angiotensinergic responses in rats submitted to low- or high-salt diet 

      Carillo, B. A.; Beutel, A.; Mirandola, D. A.; Vidonho, A. F.; Furukawa, L. N. S.; Casarini, D.; Campos, R. R.; Dolnikoff, M. S.; Heimann, J. C.; Bergamaschi, C. T. (Elsevier B.V., 2007-04-05)
      The present study was designed to evaluate, in Wistar rats, the effect of high- or low-salt diet on the hemodynamic parameters and on the renal and lumbar sympathetic nerve activity. the renal gene expression of the renin ...

    • Efeitos da angiotensina ii em modelo in vitro de hematopoiese utilizando estroma estabelecido 

      Costa, Maira Maftoum [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2013-05-29)
      A angiotensina II (AngII) é um hormônio classicamente relacionado a eventos sistêmicos, como o controle do volume de fluídos, balanço eletrolítico e pressão arterial. Alterações em sua produção ou na ativação de seus ...

    • Estudo da fibrose no músculo esquelético mediada por receptores de angiotensina e tratamento do músculo lesionado por prp e terapia gênica 

      Stilhano, Roberta Sessa [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2015-12-17)
      process, which frequently occurs in cases of deeper muscle injury, leads to imperfect tissue regeneration. The current therapies have a low efficacy for prevention or treatment of the complications caused by fibrosis, such ...

    • Hemodynamic and metabolic effects of angiotensin II on the liver 

      Nascimento, T. A.; Gioli-Pereira, L.; Carvalho, L. T.; Santos, E. L.; Pesquero, J. B.; Kouyoumdjian, M.; Borges, D. R. (Elsevier B.V., 2005-02-01)
      To ascertain the mechanism of interaction between angiotensins (AI and AII) and the liver. an angiotensin-converting enzyme inhibitor (captopril) and a receptor antagonist (losartan) were used. Monovascular or bivascular ...

    • Interaction of a non-peptide agonist with angiotensin II AT(1) receptor mutants 

      Costa-Neto, Claudio Miguel; Miyakawa, Ayumi A.; Pesquero, João Bosco [UNIFESP]; Oliveira, Laerte; Hjorth, Siv A.; Schwartz, Thue W.; Paiva, Antonio Cechelli de Mattos [UNIFESP] (Natl Research Council Canada, 2002-05-01)
      To identify residues of the rat AT(1A) angiotensin II receptor involved with signal transduction and binding of the non-peptide agonist L-162,313 (5,7-dimethyl-2-ethyl-3-[[4-[2(n-butyloxycarbonylsulfonamido)-5-isobutyl-3 ...

    • Left ventricular adaptation to chronic pressure overload induced by inhibition of nitric oxide synthase in rats 

      Matsubara, B. B.; Matsubara, L. S.; Zornoff, LAM; Franco, M.; Janicki, J. S. (Dr Dietrich Steinkopff Verlag, 1998-06-01)
    • Losartan Reduces Oxidative Stress Within the Rostral Ventrolateral Medulla of Rats With Renovascular Hypertension 

      Nishi, Erika E. [UNIFESP]; Bergamaschi, Cassia T. [UNIFESP]; Oliveira-Sales, Elizabeth B. [UNIFESP]; Simon, Karin A. [UNIFESP]; Campos, Ruy R. [UNIFESP] (Oxford Univ Press, 2013-07-01)
      Previous studies showed that the microinjection of antioxidants or the overexpression of superoxide dismutase within the rostral ventrolateral medulla (RVLM) reduces hypertension and sympathoexcitation in the 2-kidney, ...

    • Modulation of the renin-angiotensin-aldosterone system in sepsis: a new therapeutic approach? 

      Salgado, Diamantino Ribeiro; Rocco, Jose Rodolfo; Silva, Eliezer [UNIFESP]; Vincent, Jean-Louis (Informa Healthcare, 2010-01-01)
      Importance of the field: Severe sepsis is characterized by relative hypotension associated with a high cardiac output, peripheral vasodilation, and organ dysfunction. the renin-angiotensin-aldosterone system (RAAS) is ...