Browsing by Subject "amphetamine"
Now showing items 1-10 of 11
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Amphetamine- and nicotine-induced cross-sensitization in adolescent rats persists until adulthood
(Wiley-Blackwell, 2009-07-01)Nicotine and psychostimulants are often abused in combination and drug abuse often begins during adolescence and can have long-term consequences. Behavioral sensitization has been suggested as an animal model of neuroplasticity ...
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Amphetamine-induced rapid-onset sensitization: Role of novelty, conditioning and behavioral parameters
(Elsevier B.V., 2006-04-01)Background: Environmental factors may modulate sensitization to the locomotor-activating effects of psychostimulants. in addition, some parameters of locomotor activity seem to be more sensitive to detect cocaine-induced ...
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Characterization of the rapid-onset type of behavioral sensitization to amphetamine in mice: Role of drug-environment conditioning
(Nature Publishing Group, 2006-01-01)A rapid-onset type of behavioral sensitization (ROBS) has been demonstrated in rats treated with a single 'priming' injection of amphetamine (AMP). in that species, however, this phenomenon was restricted to AMP-induced ...
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Drug-induced home cage conspecifics' behavior can potentiate behavioral sensitization in mice
(Elsevier B.V., 2006-05-01)The effect of home cage conspecifics' behavior on locomotor sensitization to amphetamine (AMP) or ethanol (ETOH) were investigated. Female mice were repeatedly treated with saline or AMP (2.0 mg/kg for 13 days - Experiment ...
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Effects of amphetamine on the plus-maze discriminative avoidance task in mice
(Springer, 2002-02-01)Rationale: the contradictory amphetamine effects on memory could be due to different protocols of amphetamine administration or the well-known anxiogenic effect of the drug. Objective: the effects of different protocols ...
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Effects of microgram doses of haloperidol on open-field behavior in mice
(Elsevier B.V., 1996-04-01)This study was designed to evaluate the effects of low doses of haloperidol on the open-field behavior of mice. A three-phase effect of haloperidol on the motor activity of mice was observed (depression, no effect, ...
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Influências contextuais na sensibilização locomotora induzida pela anfetamina: o papel da generalização da memória
(Universidade Federal de São Paulo (UNIFESP), 2014-12-31)Addiction is a multifactorial disease that includes physiological mechanisms of learning and memory. Addicts have intense plasticity in cortical and limbic circuits during intoxication, abstinence or even in drug seeking ...
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Neuroleptic Drugs Revert the Contextual Fear Conditioning Deficit Presented by Spontaneously Hypertensive Rats: A Potential Animal Model of Emotional Context Processing in Schizophrenia?
(Oxford Univ Press, 2009-07-01)Schizophrenia, bipolar disorder, and attention deficit/hyperactivity disorder (ADHD) present abnormalities in emotion processing. A previous study showed that the spontaneously hypertensive rats (SHR), a putative animal ...
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Repeated monosialoganglioside administration attenuates behavioral sensitization to amphetamine
(Elsevier B.V., 1997-01-30)The effects of repeated monosialoganglioside (GM1) administration on amphetamine-induced behavioral sensitization were studied using locomotion frequency of mice observed in an open-field as an experimental parameter. GM1 ...
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Selective serotonin 2A receptor antagonism attenuates the effects of amphetamine on arousal and dopamine overflow in non-human primates
(Wiley-Blackwell, 2013-10-01)The objective of the present study was to further elucidate the mechanisms involved in the wake-promoting effects of psychomotor-stimulants. Many previous studies have tightly linked the effects of stimulants to dopamine ...
