Browsing by Subject "alternative splicing"

Now showing items 1-6 of 6

    • Cloning and characterization of an alternative splicing transcript of the gene coding for human cytidine deaminase 

      Lisboa, Blanca Cristina Garcia; Machado, Tamara da Rocha; Pimenta, Daniel Carvalho [UNIFESP]; Han, Sang Won [UNIFESP] (Natl Research Council Canada-n R C Research Press, 2007-02-01)
      Human cytidine deaminase (HCD) catalyzes the deamination of cytidine or deoxycytidine to uridine or deoxyuridine, respectively. the genomic sequence of HCD is formed by 31 kb with 4 exons and several alternative splicing ...

    • Differential expression of new LTA splice variants upon lymphocyte activation 

      Smirnova, Anna S.; Ferreira-Silva, Katia C.; Mine, Karina L.; Andrade-Oliveira, Vinicius; Shulzhenko, Natalia; Gerbase-DeLima, Maria; Morgun, Andrey (Elsevier B.V., 2008-01-01)
      Lymphotoxin alpha (LTA) is a member of the TNF cytokine superfamily, produced principally by lymphocytes. It plays an important role in immune and inflammatory responses. Many TNF superfamily members have functionally ...

    • Identification of new alternative splice events in the TCIRG1 gene in different human tissues 

      Smirnova, A. S.; Morgun, A.; Shulzhenko, N.; Silva, IDCG; Gerbase-DeLima, M. (Elsevier B.V., 2005-05-13)
      Two transcript variants (TV) of the T cell immune regulator gene 1 (TCIRG1) have already been characterized. TV1 encodes a subunit of the osteoclast vacuolar proton pump and TV2 encodes a T cell inhibitory receptor. Based ...

    • Identification of new splice variants of the genes GAFF and BCMA 

      Smirnova, Anna S. [UNIFESP]; Andrade-Oliveira, Vinicius [UNIFESP]; Gerbase-DeLima, Maria [UNIFESP] (Elsevier B.V., 2008-02-01)
      The TNF superfamily ligands BAFF and APRIL and receptors BCMA, TACT and BAFF-R play an important role in the regulation of B cell immunity. A number of functionally important splice isoforms have already been characterized ...

    • Structure and expression of two kininogen genes in mice 

      Cardoso, C. C.; Garrett, T.; Cayla, C.; Meneton, P.; Pesquero, J. B.; Bader, M. (Walter de Gruyter & Co, 2004-03-01)
      Kininogens serve dual functions by forming a scaffold for the assembly of the protein complex initiating the surfaceactivated blood coagulation cascade and as precursors for the kinin hormones. While rats have three kininogen ...

    • Tissue-specific expression of IL-15RA alternative splicing transcripts and its regulation by DNA methylation 

      Diniz, Susana N. [UNIFESP]; Pendeloski, Karen P. T. [UNIFESP]; Morgun, Andrey [UNIFESP]; Chepelev, Iouri; Gerbase-DeLima, Maria [UNIFESP]; Shulzhenko, Natalia [UNIFESP] (John Libbey Eurotext Ltd, 2010-12-01)
      The human IL-15RA gene encoding the alpha chain of the IL-15 receptor is expressed in a variety of immune and non-immune cell types from different tissues, and generates multiple splicing events of functional importance. ...