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    • Use of transgenic (knockout) mice reveals a site distinct from the alpha(2A)-adrenoceptors for agmatine in the vas deferens 

      Santos, Wilson da Costa; Garcez-do-Carmo, Lucia [UNIFESP]; Silva, Eliane Cristina da [UNIFESP]; Pascual, Ricardo de; Jurkiewicz, Neide Hyppolito [UNIFESP]; Jurkiewicz, Aron [UNIFESP]; Gandia, Luis (Polish Acad Sciences Inst Pharmacology, 2009-03-01)
      The inhibitory effect of agmatine on electrically induced contractions was studied in vas deferens of Adra 2a transgenic mice lacking alpha(2A)-adrenoceptors. Agmatine and clonidine caused a concentration-dependent inhibition ...