Now showing items 1-10 of 10

    • Avaliação das etapas de ativação dos inflamassomas em astrócitos em resposta ao Zika vírus 

      Lucena, Victoria Weise Leite de [UNIFESP] (Universidade Federal de São Paulo, 2023-12-12)
      Os inflamassomas são complexos citosólicos multiproteicos ativados em resposta a infecções ou danos celulares. A ativação dessas plataformas leva ao recrutamento e autoclivagem da protease efetora caspase-1 e consequente ...

    • Caracterização das manifestações oftalmológicas na síndrome congênita do zika vírus 

      Ventura, Camila Vieira Oliveira Carvalho [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-01-18)
      Objectives: To characterize the ocular abnormalities identified in infants with Congenital Zika Syndrome (CZS). For this purpose, three studies were conducted with the following specific objectives: 1 - To describe the ...

    • Epitope Sequences in Dengue Virus NS1 Protein Identified by Monoclonal Antibodies 

      Rocha, Leticia Barboza; dos Santos Alves, Rubens Prince; Caetano, Bruna Alves; Pereira, Lennon Ramos; Mitsunari, Thais; Amorim, Jaime Henrique; Polatto, Juliana Moutinho; Botosso, Viviane Fongaro; Frazatti Gallina, Neuza Maria; Palacios, Ricardo; Precioso, Alexander Roberto; Hernandes Granato, Celso Francisco [UNIFESP]; Leal Oliveira, Danielle Bruna; da Silveira, Vanessa Barbosa; Luz, Daniela; de Souza Ferreira, Luis Carlos; Fontes Piazza, Roxane Maria (Mdpi Ag, 2017)
      Dengue nonstructural protein 1 (NS1) is a multi-functional glycoprotein with essential functions both in viral replication and modulation of host innate immune responses. NS1 has been established as a good surrogate marker ...

    • High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti 

      Torquato, Ricardo J. S. [UNIFESP]; Lu, Stephen [UNIFESP]; Martins, Nadia Helena; Tanaka, Aparecida S. [UNIFESP]; Barbosa Pereira, Pedro Jose (Int Union Crystallography, 2017)
      Blood-feeding exoparasites are rich sources of protease inhibitors, and the mosquito Aedes aegypti, which is a vector of Dengue virus, Yellow fever virus, Chikungunya virus and Zika virus, is no exception. AaTI is a ...

    • Ocular effects of Zika virus-a review 

      Marquezan, Maria Carolina [UNIFESP]; Ventura, Camila V. [UNIFESP]; Sheffield, Jeanne S.; Golden, William Christopher; Omiadze, Revaz; Belfort, Rubens, Jr. [UNIFESP]; May, William (Elsevier Science Inc, 2018)
      Zika virus was considered an innocent pathogen while restricted to the African and Asian population

    • On the origin and timing of Zika virus introduction in Brazil 

      Massad, E.; Burattini, Marcelo Nascimento [UNIFESP]; Khan, K.; Struchiner, C. J.; Coutinho, F. A. B.; Wilder-Smith, A. (Cambridge Univ Press, 2017)
      The timing and origin of Zika virus (ZIKV) introduction in Brazil has been the subject of controversy. Initially, it was assumed that the virus was introduced during the FIFA World Cup in June-July 2014. Then, it was ...

    • Potencial diagnóstico e vacinal de derivados da proteína de envelope (E) do vírus Zika produzidos em procarioto e eucarioto 

      Lunardelli, Victória Alves Santos [UNIFESP] (Universidade Federal de São Paulo, 2022-12-01)
      No presente estudo, avaliamos o potencial diagnóstico e vacinal de diferentes proteínas recombinantes do vírus Zika (ZIKV) produzidas em sistema procarioto (Eschericha coli) e eucarioto (células S2 de Drosophila melanogaster). ...

    • Zika virus and pregnancy in Brazil: What happened? 

      Pereira, Alessandra Mendelski; Maia Monteiro, Denise Leite; Werner, Heron; Daltro, Pedro; Fazecas, Tatiana; Guedes, Bianca; Tonni, Gabriele; Peixoto, Alberto Borges; Araujo Junior, Edward [UNIFESP] (Galenos Yayincilik, 2018)
      The recent epidemic of Zika virus (ZIKV) infection in Central and South America is one of the most serious global public health emergencies since the Ebola outbreak in West Africa. In Brazil, especially in the north, ...

    • Zika virus and the eye 

      Freitas, Bruno de Paula [UNIFESP]; Ventura, Camila V. [UNIFESP]; Maia, Mauricio [UNIFESP]; Belfort, Rubens, Jr. [UNIFESP] (Lippincott Williams & Wilkins, 2017)
      Purpose of review The aim of this study was to review the ocular findings related to the Zika virus (ZIKV) based on the main studies published to date, describe the patterns of the lesions and risk factors, and identify ...

    • Zika Virus Outbreak - Should assisted reproduction patients avoid pregnancy? 

      Borges, Edson, Jr.; de Almeida Ferreira Braga, Daniela Paes [UNIFESP]; Zanetti, Bianca Ferrarini; Setti, Amanda Souza; Provenza, Rodrigo Rosa; Iaconelli, Assumpto, Jr. (Soc Brasileira Reproducao Assistida-Sbra, 2017)
      Objective: To discuss the requirement from the National Health Surveillance Agency(ANVISA), for assisted reproduction treatment patients to undergo laboratory tests for ZIKV detection, and if the public health authorities ...