Now showing items 1-6 of 6

    • Ascorbic acid reduces gentamicin-induced nephrotoxicity in rats through the control of reactive oxygen species 

      Moreira, Miriam A.; Nascimento, Marcos A.; Bozzo, Tatiana A.; Cintra, Alvaro [UNIFESP]; Silva, Sonia M. da [UNIFESP]; Dalboni, Maria Aparecida [UNIFESP]; Mouro, Margaret G.; Higa, Elisa M. S. [UNIFESP] (Churchill Livingstone, 2014-04-01)
      Background & aim: Oxidative stress has been implicated in the pathophysiology of many forms of acute renal failure. the aim was examine the effect of vitamin C on oxidative stress and its relationship with nitric oxide on ...

    • Beneficial effects of vitamin C and vitamin E on reserpine-induced oral dyskinesia in rats: Critical role of striatal catalase activity 

      Faria, Rulian Ricardo [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP]; Grassl, Christian [UNIFESP]; Chinen, Cibele Cristina [UNIFESP]; Negrão, Luciana Takahashi Ribeiro [UNIFESP]; Castro, Juliana Pedroso Moraes Vilela de [UNIFESP]; Fukushiro, Daniela Fukue [UNIFESP]; Rodrigues, Marcelo Scarpari Dutra [UNIFESP]; Gomes, Patricia Helena Zanier [UNIFESP]; Registro, Sibele [UNIFESP]; Carvalho, Rita de Cassia [UNIFESP]; D'Almeida, Vania [UNIFESP]; Silva, Regina Helena [UNIFESP]; Ribeiro, Rosana de Alencar [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 2005-06-01)
      Oral dyskinesias are implicated in a series of neuropathologies and have been associated to an increase in oxidative stress. Several antioxidants, including vitamin E, decrease reserpine-induced oral clyskinesia (OD) in ...

    • Cardioprotective Actions of Ascorbic Acid during Isoproterenol-Induced Acute Myocardial Infarction in Rats 

      Buttros, Juliana Beatriz [UNIFESP]; Bergamaschi, Cassia Toledo [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Fracalossi, Ana Carolina Cuzzuol [UNIFESP]; Campos, Ruy Ribeiro [UNIFESP] (Karger, 2009-01-01)
      Background/Aims: in the present study, we tested whether or not acute antioxidant treatment with vitamin C is able to protect the heart during myocardial infarction. the effects of vitamin C on the autonomic balancing of ...

    • Chronic supplementation of creatine and vitamins C and E increases survival and improves biochemical parameters after doxorubicin treatment in rats 

      Santos, Ronaldo Vagner Thomatieli dos [UNIFESP]; Batista, Miguel L.; Caperuto, Erico C.; Costa Rosa, Luis F. B. P. (Blackwell Publishing, 2007-12-01)
      1. Doxorubicin is an anti-cancer drug with well-described effects against a wide range of tumours. However, doxorubicin also exhibits dose-dependent cytotoxicity. the purpose of the present study was to determine whether ...

    • Efeitos cardiovasculares ao tratamento crônico com vitamina C na hipertensão renovascular em ratos Wistar 

      Nishi, Erika Emy [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-01-27)
      Sympathetic vasomotor hyperactivity and baroreflex dysfunction are involved in the development and maintenance of Goldblatt 2 kidney, 1 clip (2K-1C) model of renovascular arterial hypertension (AH). This experimental model ...

    • Preoperative vitamin C supplementation improves colorectal anastomotic healing and biochemical parameters in malnourished rats 

      Danielski, Lucineia Gainski; Walczewski, Eduardo; de Jesus, Clovisa Reck; Florentino, Drielly; Della Giustina, Amanda; Goldim, Mariana Pereira; Kanis, Luiz Alberto; Pereira, Gregório Wrublevski [UNIFESP]; Pereira, Volnei D.; Felisberto, Francine; Petronilho, Fabricia (Springer, 2016)
      The objective of this study was to evaluate the effect of supplementation with vitamin C on intestinal anastomosis healing in malnourished rats. Male Wistar rats were divided into three groups: (1) sham, well-nourished ...