Now showing items 1-7 of 7

    • The adjuvanticity of Chiococca alba saponins increases with the length and hydrophilicity of their sugar chains 

      Nico, Dirlei; Borges, Ricardo Moreira; Brandao, Layza Mendes; Feijo, Daniel Ferreira; Gomes, Daniele Crespo; Palatnik, Marcos; Rodrigues, Mauricio Martins [UNIFESP]; Ribeiro da Silva, Antonio Jorge; Palatnik-de-Sousa, Clarisa Beatriz (Elsevier B.V., 2012-05-02)
      The saponins of Chiococca alba are triterpene bidesmosides that contain glycidic moieties attached to the C-3 and C-28 carbon of their aglycone. We describe that their adjuvant potential increases in direct relationship ...

    • An antigenic domain within a catalytically active Leishmania infantum nucleoside triphosphate diphosphohydrolase (NTPDase 1) is a target of inhibitory antibodies 

      Ribeiro Gomes Maia, Ana Carolina; Porcino, Gabriane Nascimento; Detoni, Michelle de Lima; Emidio, Nayara Braga; Marconato, Danielle Gomes; Faria-Pinto, Priscila; Fessel, Melissa Regina; Reis, Alexandre Barbosa; Juliano, Luiz [UNIFESP]; Juliano, Maria Aparecida [UNIFESP]; Marques, Marcos Jose; Vasconcelos, Eveline Gomes (Elsevier B.V., 2013-02-01)
      We identified a shared B domain within nucleoside triphosphate diphosphohydrolases (NTPDases) of plants and parasites. Now, an NTPDase activity not affected by inhibitors of adenylate kinase and ATPases was detected in ...

    • Epidemiologic, clinical, diagnostic and therapeutic aspects of visceral leishmaniasis in renal transplant recipients: experience from thirty cases 

      Silva, Avelar Alves de; Pacheco-Silva, Alvaro [UNIFESP]; Sesso, Ricardo de Castro Cintra [UNIFESP]; Esmeraldo, Ronaldo de Matos; Oliveira, Claudia Maria Costa de; Fernandes, Paula Frassinetti Castelo Branco Camurca; Oliveira, Rodrigo Alves de; Silva, Leila Silveira Veira de; Carvalho, Valencio Pereira de; Costa, Carlos Henrique Nery; Andrade, Jesusmar Ximenes; Silva, Diana Marisa Barros da; Chaves, Roosevelt Valente (Biomed Central Ltd, 2015-02-25)
      Background: Visceral leishmaniasis is a disease caused by the protozoan Leishmania sp. and is transmitted by Lutzomyia longipalpis (sand fly). in renal transplant recipients, visceral leishmaniasis causes severe damage to ...

    • Historical series of patients with visceral leishmaniasis treated with meglumine antimoniate in a hospital for tropical diseases, Maceió-AL, Brazil 

      Silveira, Lindon Johoson Diniz [UNIFESP]; Rocha, Thiago José Matos; Ribeiro, Sandra Aparecida [UNIFESP]; Pedrosa, Célia Maria Silva (Instituto de Medicina Tropical, 2015-02-01)
      Introduction: Visceral leishmaniasis is an endemic protozoan found in Brazil. It is characterized by fever, pallor, hepatosplenomegaly, lymphadenopathy, and progressive weakness in the patient. It may lead to death if ...

    • Nível sérico da vitamina A em crianças portadoras de leishmaniose visceral 

      Luz, Kleber Giovanni; Succi, Regina Célia de Menezes [UNIFESP]; Torres, Elizabeth (Sociedade Brasileira de Medicina Tropical - SBMT, 2001-08-01)
      Vitamin A is considered an anti-infectious disease vitamin, and its deficiency is associated with severe infections such as in measles. In developing countries the low concentrations of vitamin A are a public health problem. ...

    • The Risk Factors for and Effects of Visceral Leishmaniasis in Graft and Renal Transplant Recipients 

      Silva, Avelar Alves da [UNIFESP]; Pacheco-Silva, Alvaro [UNIFESP]; Cintra Sesso, Ricardo de Castro [UNIFESP]; Esmeraldo, R. M.; Costa de Oliveira, Claudia Maria; Fernandes, P. F. C. B. C.; Oliveira, R. A.; Silva, L. S. V.; Carvalho, Valencio P.; Nery Costa, Carlos Henrique (Lippincott Williams & Wilkins, 2013-03-15)
      Background. the aim of this study was to identify the risk factors for visceral leishmaniasis (VL) in renal transplant recipients and to analyze the impacts of this disease on graft success and patient health.Methods. This ...

    • Série histórica de pacientes com Leishmaniose visceral tratados com antimoniato de meglumina 

      Silveira, Lindon Johoson Diniz [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-11-24)
      Introduction: Visceral Leishmaniasis (VL) is an endemic disease found in Brazil mainly in Northeast region. These protozoosis is an infection, systemic, chronic disease characterized by fever, hepatosplenomegaly and increase ...