Browsing by Subject "Urethane"

Now showing items 1-4 of 4

    • Avaliação da evolução do tumor pulmonar experimental induzido por uretana em camundongos sedentários Santos 

      Tomás, Caio Marins [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2013-02-18)
      Tumores “escapam” da função antitumoral pela secreção de fatores que inibem o sistema imune. Um efeito dos fatores secretados pelo tumor é o aumento das células mieloides supressoras (MDSC) que suprimem a resposta imune ...

    • FTY720 and lung tumor development 

      Antunes Salinas, Natalia Regina [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Cury, Patricia Maluf; Cordeiro, Jose Antonio; Bueno, Valquiria [UNIFESP] (Elsevier B.V., 2009-06-01)
      FTY720 has been shown to prevent cancer development in experimental models but there is no report whether this beneficial effect is associated with the time point of the drug administration. Lung adenoma was induced in ...

    • Identification of myeloid-derived suppressor cells and T regulatory cells in lung microenvironment after Urethane-induced lung tumor 

      Perillo Rosin, Flavia Cristina [UNIFESP]; Pedregosa, Juliana Figueredo [UNIFESP]; Almeida, Joaquim Soares de [UNIFESP]; Bueno, Valquiria [UNIFESP] (Elsevier B.V., 2011-07-01)
      Tumor growth occurs by the imbalance between cells with effector function and cells with suppressor/regulatory functions. To investigate this scenario we administered the chemical carcinogen Urethane in BALB/c mice and ...

    • Lung Tumor Development in the Presence of Sphingosine 1-phosphate Agonist FTY720 

      Salinas, Natalia Regina Antunes [UNIFESP]; Lopes, Camila Takao [UNIFESP]; Palma, Patricia V.; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Bueno, Valquiria [UNIFESP] (Springer, 2009-12-01)
      Urethane is a chemical carcinogen which causes lung tumorigenesis in mice with similarities to human adenocarcinoma (AC). the sphingosine 1-phosphate agonist FTY720 administered to mice in doses above 5 mg/kg/day has been ...