Now showing items 1-5 of 5

    • The defensive functions of plant inhibitors are not restricted to insect enzyme inhibition 

      Sumikawa, Joana Tomomi; Brito, Marlon Vilela de; Rodrigues Macedo, Maria Ligia; Uchoa, Adriana F.; Miranda, Antonio [UNIFESP]; Araujo, Ana Paula U.; Silva-Lucca, Rosemeire A.; Sampaio, Misako Uemura; Oliva, Maria Luiza Vilela [UNIFESP] (Elsevier B.V., 2010-02-01)
      Three plant proteinase inhibitors BbKI (kallikrein inhibitor) and BbCI (cruzipain inhibitor) from Bauhinia bouhinioides, and a BrTI (trypsin inhibitor) from B. rufa, were examined for other effects in Callosobruchus maculatus ...

    • Interaction of proteinase inhibitors with phospholipid vesicles is modulated by pH 

      Silva-Lucca, Rosemeire A. [UNIFESP]; Faneca, Henrique M. S.; Pedroso de Lima, Maria C.; De Caroli, Fernanda P. [UNIFESP]; Assis, M. L. [UNIFESP]; Sampaio, Misako U. [UNIFESP]; Oliva, Maria Luiza V. [UNIFESP] (Elsevier B.V., 2010-11-01)
      rBbKI and rBbCI, plant recombinant inhibitors from Bauhinia bauhinioides, and BpuTI from Bauhinia purpurea seeds distinctly and specifically block proteolytic enzymes. the secondary structures of those inhibitors were ...

    • The Kallikrein Inhibitor from Bauhinia bauhinioides (BbKI) shows antithrombotic properties in venous and arterial thrombosis models 

      Brito, Marlon V. [UNIFESP]; Oliveira, Cleide de [UNIFESP]; Salu, Bruno R. [UNIFESP]; Andrade, Sonia A.; Malloy, Paula M. D. [UNIFESP]; Sato, Ana C. [UNIFESP]; Vicente, Cristina P.; Sampaio, Misako U. [UNIFESP]; Maffei, Francisco H. A. [UNIFESP]; Oliva, Maria Luiza V. [UNIFESP] (Elsevier B.V., 2014-05-01)
      The Bauhinia bauhinioides Kallikrein Inhibitor (BbKI) is a Kunitz-type serine peptidase inhibitor of plant origin that has been shown to impair the viability of some tumor cells and to feature a potent inhibitory activity ...

    • A novel trypsin Kazal-type inhibitor from Aedes aegypti with thrombin coagulant inhibitory activity 

      Watanabe, Renata M. O. [UNIFESP]; Soares, Tatiane S. [UNIFESP]; Morais-Zani, Karen; Tanaka-Azevedo, Anita M.; Maciel, Ceres; Capurro, Margareth L.; Torquato, Ricardo J. S. [UNIFESP]; Tanaka, Aparecida S. [UNIFESP] (Elsevier B.V., 2010-08-01)
      Kazal-type inhibitors play several important roles in invertebrates, such as anticoagulant, vasodilator and antimicrobial activities. Putative Kazal-type inhibitors were described in several insect transcriptomes. in this ...

    • A Trypsin Inhibitor from Sapindus saponaria L. Seeds: Purification, Characterization, and Activity Towards Pest Insect Digestive Enzyme 

      Macedo, Maria Ligia R.; Diz Filho, Eduardo B. S.; Freire, Mariadas Gracas M.; Oliva, Maria Luiza V. [UNIFESP]; Sumikawa, Joana T. [UNIFESP]; Toyama, Marcos H.; Marangoni, Sergio (Springer, 2011-01-01)
      The present paper describes the purification, characterization and determination of the partial primary structure of the first trypsin inhibitor isolated from the family Sapindaceae. A highly stable, potent trypsin inhibitor ...