Browsing by Subject "Traumatic brain injury"
Now showing items 1-4 of 4
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Chondroitin Sulfate Impairs Neural Stem Cell Migration Through ROCK Activation
(Humana Press Inc, 2018)Brain injuries such as trauma and stroke lead to glial scar formation by reactive astrocytes which produce and secret axonal outgrowth inhibitors. Chondroitin sulfate proteoglycans (CSPG) constitute a well-known class of ...
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Fluid Resuscitation With Isotonic or Hypertonic Saline Solution Avoids Intraneural Calcium Influx After Traumatic Brain Injury Associated With Hemorrhagic Shock
(Lippincott Williams & Wilkins, 2010-04-01)Background: Calcium is one of the triggers involved in ischemic neuronal death. Because hypotension is a strong predictor of outcome in traumatic brain injury (TBI), we tested the hypothesis that early fluid resuscitation ...
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Notch, Wnt and Shh neurogenic signaling co-regulation in reactive astrocyte response
(Universidade Federal de São Paulo, 2022-05-09)After a TBI, the neural network activates a reparative response seeking to restore homeostasis in the affected area. Astrocyte reactivation is an essential component of this response. Understanding astroglial cell ...
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Value of Repeat Cranial Computed Tomography in Pediatric Patients Sustaining Moderate to Severe Traumatic Brain Injury
(Lippincott Williams & Wilkins, 2008-12-01)Background: Repeat head computed tomography (CT) is standard practice for traumatic brain injury (TBI) at many centers. the few studies available in children remain unclear over the value of repeat CT within 24 hours to ...