Browsing by Subject "Terapia de genes"

Now showing items 1-6 of 6

    • Avaliação do vetor retroviral bicistrônico Codificador de endostatina e interleucina-2 Para utilização em terapia gênica anti-tumoral 

      Rocha, Flavia Gomes de Goes [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-07-28)
      Gene therapy has been used in preclinical studies and clinical trials in order to assuage or cure a disease. Retroviral vectors are tools for gene transfer are widely used. Bicistronic vectors are attractive alternatives ...

    • Fator de crescimento do endotélio vascular na viabilidade do retalho musculofasciocutâneo transverso do reto do abdome, em ratos submetidos à nicotina 

      Silveira, Tiago Santos [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2009-07-30)
      Introduction: Several factors can reduce the viability of the TRAM flap, among them the nicotine has been made responsible by the loss partial or total of these flaps. Objective: To evaluate the action of the Vascular ...

    • Gene transfer to primary corneal epithelial cells with an integrating lentiviral vector 

      Oliveira, Lauro Augusto De [UNIFESP]; Kim, Charles; Sousa, Luciene Barbosa De [UNIFESP]; Schwab, Ivan R.; Rosenblatt, Mark I. (Conselho Brasileiro de Oftalmologia, 2010-10-01)
      PURPOSE: To evaluate the transfer of heterologous genes carrying a Green Fluorescent Protein (GFP) reporter cassette to primary corneal epithelial cells ex vivo. METHODS: Freshly enucleated rabbit corneoscleral tissue was ...

    • Terapia gênica com VEGF para angiogênese na angina refratária: ensaio clínico fase I/II 

      Kalil, Renato A. K.; Salles, Felipe Borsu De; Giusti, Imarilde Inês; Rodrigues, Clarissa Garcia; Han, Sang Won [UNIFESP]; Sant'anna, Roberto Tofani; Ludwig, Eduardo; Grossman, Gabriel; Prates, Paulo Roberto Lunardi; Sant'anna, João Ricardo Michelin; Teixeira Filho, Guaracy Fernandes; Nardi, Nance Beyer; Nesralla, Ivo Abrahão (Sociedade Brasileira de Cirurgia Cardiovascular, 2010-09-01)
      OBJECTIVE: Safety, feasibility and early myocardial angiogenic effects evaluation of transthoracic intramyocardial phVEGF165 administration for refractory angina in no option patients. METHODS: Cohort study, in which 13 ...

    • Terapia gênica em distrofias hereditárias de retina 

      Côco, Monique [UNIFESP]; Han, Sang Won [UNIFESP]; Sallum, Juliana Maria Ferraz (Conselho Brasileiro de Oftalmologia, 2009-08-01)
      The inherited retinal dystrophies comprise a large number of disorders characterized by a slow and progressive retinal degeneration. They are the result of mutations in genes that express in either the photoreceptor cells ...

    • Terapia gênica para osteoporose 

      Costa, Rafael Pacheco da [UNIFESP]; Han, Sang Won [UNIFESP]; Pochini, Alberto de Castro [UNIFESP]; Reginato, Rejane Daniele [UNIFESP] (Sociedade Brasileira de Ortopedia e Traumatologia, 2011-01-01)
      Osteoporosis is considered one of the most common and serious problems affecting the elderly population worldwide. It is a chronic and progressive disease, characterized by decreased bone mass and degeneration of the ...