Browsing by Subject "Tacrolimus"

Now showing items 1-10 of 10

    • Avaliação da eficácia e segurança do tacrolimo pomada 0,03% no tratamento da dermatite atópica em pacientes pediátricos 

      Gontijo, Bernardo; Duarte, Ida A. Gomes; Sittart, José Alexandre de Souza; Pires, Mario Cezar; Takaoka, Roberto; Cestari, Silmara da Costa Pereira [UNIFESP]; Cestari, Tania Ferreira; Aun, Wilson Tartuce; Oliveira, Zilda Najjar P. de; La Scala, Cintia Sayuri Kurokawa [UNIFESP] (Sociedade Brasileira de Dermatologia, 2008-12-01)
      BACKGROUND: Tacrolimus ointment has been shown to be effective in treatment of atopic dermatitis. OBJECTIVES: To evaluate the efficacy and safety of 0.03% tacrolimus ointment (Protopic®) in pediatric patients with mild, ...

    • Basiliximab induction in patients receiving tacrolimus-based immunosuppressive regimens 

      Sandes-Freitas, Taina Veras de [UNIFESP]; Felipe, Claudia Rosso [UNIFESP]; Franco, Marcello Fabiano de [UNIFESP]; Tedesco-Silva, Helio [UNIFESP]; Medina-Pestana, Jose Osmar [UNIFESP] (Springer, 2013-04-01)
      The use of basiliximab induction increased significantly in recent years based on its superior efficacy and excellent safety profile demonstrated in studies with cyclosporine-based immunosuppression. However, its clinical ...

    • Desenvolvimento de metodologia quantitativa por MALDI-MS para determinação de imunossupressores 

      Lavorenti, Julia [UNIFESP] (Universidade Federal de São Paulo, 2022-11-25)
      Os transplantes de órgãos se tornaram um processo rotineiro nos hospitais graças ao avanço dos estudos sobre o corpo humano e das técnicas cirúrgicas, além do desenvolvimento de imunossupressores. Dentre os milhares de ...

    • Donor-Specific Anti-Human Leukocyte Antigens Antibodies, Acute Rejection, Renal Function, and Histology in Kidney Transplant Recipients Receiving Tacrolimus and Everolimus 

      Ferreira, Alexandra Nicolau [UNIFESP]; Felipe, Claudia Rosso [UNIFESP]; Cristelli, Marina Pontello [UNIFESP]; Viana, Laila [UNIFESP]; Basso, Geovana [UNIFESP]; Stopa, Suelen[UNIFESP]; Mansur, Juliana Busato [UNIFESP]; Paula, Mayara Ivani de [UNIFESP]; Bessa, Adrieli Barros [UNIFESP]; Ruiz, Priscila Ruppel [UNIFESP]; Aguiar, Wilson Ferreira [UNIFESP]; Campos, Erika Fernandes [UNIFESP]; Gerbase-Lima, Maria [UNIFESP]; Proença, Henrique [UNIFESP]; Tedesco-Silva, Helio [UNIFESP]; Pestana, Jose Osmar Medina [UNIFESP] (Karger, 2017)
      Background: This analysis compared efficacy, renal function, and histology in kidney transplant recipients receiving tacrolimus (TAC) combined with everolimus (EVR) or mycophenolate (MPS). Methods: This was a retrospective ...

    • Exploratory calcineurin inhibitor-free regimens in living-related kidney transplant recipients 

      Garcia, Riberto [UNIFESP]; Machado, Paula Goulart Pinheiro [UNIFESP]; Felipe, Claudia Rosso [UNIFESP]; Park, Sung In [UNIFESP]; Spinelli, Glaucio Amaral [UNIFESP]; Franco, Marcello Fabiano de [UNIFESP]; Tedesco-Silva Junior, Hélio [UNIFESP]; Pestana, Jose Osmar Medina [UNIFESP] (Associação Brasileira de Divulgação Científica, 2007-04-01)
      Chronic allograft nephropathy is among the major causes of graft loss even in low-risk kidney transplant recipients and correlates with acute nephrotoxic events during the first year post-transplant. Therefore, calcineurin ...

    • Impact of initial exposure to calcineurin inhibitors on kidney graft function of patients at high risk to develop delayed graft function 

      Silva, Laercio A. [UNIFESP]; Felipe, Claudia Rosso [UNIFESP]; Park, Sung In [UNIFESP]; Machado, Paula Goulart Pinheiro [UNIFESP]; Garcia, Riberto [UNIFESP]; Franco, Marcello Fabiano de [UNIFESP]; Moreira, Silvia Regina Silva [UNIFESP]; Tedesco-Silva Junior, Hélio [UNIFESP]; Pestana, Jose Osmar Medina [UNIFESP] (Associação Brasileira de Divulgação Científica, 2006-01-01)
      We conducted a retrospective analysis of the influence of full doses of calcineurin inhibitors [8-10 mg kg-1 day-1 cyclosporine (N = 80), or 0.2-0.3 mg kg-1 day-1 tacrolimus (N = 68)] administered from day 1 after ...

    • Interaction of the Anti-Inflammatory Annexin A1 Protein and Tacrolimus Immunosuppressant in the Renal Function of Rats 

      Araujo, Leandro P. [UNIFESP]; Truzzi, Renata R.; Mendes, Gloria E.; Luz, Marcus A. M.; Burdmann, Emmanuel A.; Oliani, Sonia M. [UNIFESP] (Karger, 2010-01-01)
      Background: Tacrolimus (FK) is currently widely used in transplant immunosuppression and the treatment of autoimmune diseases. However, FK induces nephrotoxicity which is characterized by functional and structural renal ...

    • Interação farmacocinética do tacrolimo: a influência de prednisona, ácido micofenólico ou sirolimo 

      Park, Sung In [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-07-28)
      Background & objective: This study was conducted to evaluate timedependent pharmacokinetic changes and drug interactions over the first 6 months after transplantation in kidney transplant recipients receiving tacrolimus, ...

    • Remote ischemic preconditioning and tacrolimus in the fetal small bowel transplant in mice 

      Morello, Ricardo José [UNIFESP]; Koike, Marcia Kiyomi; Abrahão, Marcos de Souza [UNIFESP]; Saad, Karen Ruggeri; Saad, Paulo Fernandes; Montero, Edna Frasson de Souza [UNIFESP] (Acta Cirurgica Brasileira, 2016)
      PURPOSE: To evaluate the effect of remote ischemic preconditioning (IPC-R) in the fetal small bowel transplantation model. METHODS: Two groups were constituted: The Isogenic transplant (ISO, C57BL/6 mice, n=24) and the ...

    • Tacrolimus eye drops as monotherapy for vernal keratoconjunctivitis: a randomized controlled trial 

      Mueller, Eduardo Gayger [UNIFESP]; dos Santos, Myrna Serapiao [UNIFESP]; Freitas, Denise [UNIFESP]; Pereira Gomes, Jose Alvaro [UNIFESP]; Belfort, Rubens, Jr. [UNIFESP] (Consel Brasil Oftalmologia, 2017)
      Purpose: To assess the efficacy of monotherapy using tacrolimus eye drops versus sodium cromoglycate for the treatment of vernal keratoconjunctivitis (VKC). Methods: Randomized double-masked controlled trial comparing the ...