Browsing by Subject "Spontaneously hypertensive rats"

Now showing items 1-7 of 7

    • Effect of antipsychotic drugs on gene expression in the prefrontal cortex and nucleus accumbens in the spontaneously hypertensive rat (SHR) 

      Santoro, Marcos Leite [UNIFESP]; Ota, Vanessa Kiyomi [UNIFESP]; Stilhano, Roberta Sessa [UNIFESP]; Silva, Patricia Natalia [UNIFESP]; Santos, Camila Mauricio [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Gadelha, Ary [UNIFESP]; Bressan, Rodrigo Affonseca [UNIFESP]; Melaragno, Maria Isabel [UNIFESP]; Han, Sang Won [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP]; Belangero, Sintia Iole [UNIFESP] (Elsevier B.V., 2014-08-01)
      Antipsychotic drugs (APDs) are the standard treatment for schizophrenia. the therapeutic effect of these drugs is dependent upon the dopaminergic D2 blockade, but they also modulate other neurotransmitter pathways. the ...

    • The Effects of Physical Exercise on the Serum Iron Profile in Spontaneously Hypertensive Rats 

      Frank, Miriam K. [UNIFESP]; Esteves, Andrea Maculano [UNIFESP]; Lopes, Cleide [UNIFESP]; Cavagnolli, Daniel A. [UNIFESP]; Tufik, Sergio [UNIFESP]; Mello, Marco Tulio de [UNIFESP] (Humana Press Inc, 2012-02-01)
      The purpose of this study was to evaluate the profile of serum iron in spontaneously hypertensive rats after an aerobic physical exercise. To accomplish this, 12 normotensive Wistar rats and 12 spontaneously hypertensive ...

    • Expression profile of neurotransmitter receptor and regulatory genes in the prefrontal cortex of spontaneously hypertensive rats: Relevance to neuropsychiatric disorders 

      Santoro, Marcos Leite [UNIFESP]; Santos, Camila Mauricio [UNIFESP]; Ota, Vanessa Kiyomi [UNIFESP]; Gadelha, Ary [UNIFESP]; Stilhano, Roberta Sessa [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Silva, Patricia Natalia [UNIFESP]; Nery Spindola, Leticia Maria [UNIFESP]; Melaragno, Maria Isabel [UNIFESP]; Bressan, Rodrigo Affonseca [UNIFESP]; Han, Sang Won [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP]; Belangero, Sintia Iole [UNIFESP] (Elsevier B.V., 2014-11-30)
      The spontaneously hypertensive rat (SHR) strain was shown to be a useful animal model to study several behavioral, pathophysiological and pharmacological aspects of schizophrenia and attention-deficit/hyperactivity disorder. ...

    • Kinin receptors of the central-nervous-system of spontaneously hypertensive rats related to the pressor-response to bradykinin 

      Martins, Domingos Tabajara de Oliveira [UNIFESP]; Fior-Chadi, Debora Rejane [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP]; Lindsey, Charles Julian [UNIFESP] (Stockton Press, 1991-08-01)
      1 Kinin analogues bradykinin (BK), T-kinin, Met-Lys-BK, Lys-Lys-BK, Des-Arg9-BK with agonist activity and D-Arg0-Hyp3-Thi5,8-D-Phe7-BK (DAHTDBK) and Arg9-Leu8-BK with antagonist activity were injected into the posterior ...

    • Renin angiotensin system and cardiac hypertrophy after sinoaortic denervation in rats 

      Piratello, Aline Cristina [UNIFESP]; Moraes-Silva, Ivana Cinthya [UNIFESP]; Paulini, Janaina; Souza, Pamella Ramona; Sirvente, Raquel; Salemi, Vera; Flues, Karin; Moreira, Edson Dias; Mostarda, Cristiano [UNIFESP]; Cunha, Tatiana Sousa [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Irigoyen, Maria Claudia [UNIFESP] (Faculdade de Medicina / USP, 2010-01-01)
      OBJECTIVE: The aim of this study was to evaluate the role of angiotensin I, II and 1-7 on left ventricular hypertrophy of Wistar and spontaneously hypertensive rats submitted to sinoaortic denervation. METHODS: Ten weeks ...

    • Sleep-related movement disorder symptoms in SHR are attenuated by physical exercise and an angiotensin-converting enzyme inhibitor 

      Frank, Miriam Kannebley; Mello, Marco Tulio de; Lee, Kil Sun [UNIFESP]; Daubian-Nose, Paulo; Tufik, Sergio [UNIFESP]; Esteves, Andrea Maculano (Pergamon-Elsevier Science Ltd, 2016)
      The relationship between hypertension and sleep-related movement disorders has been hypothesized for humans, but the causes and mechanisms have not been elucidated. We investigated whether an alteration in blood pressure ...

    • Structural properties of lipid reconstructs and lipid composition of normotensive and hypertensive rat vascular smooth muscle cell membranes 

      Oliveira, Tiago.Ribeiro de; Lamy, Maria Teresa; De Paula, Urdiel Macedo [UNIFESP]; Guimarães, Luciana Lopes [UNIFESP]; Toledo, Marcos Sergio de [UNIFESP]; Takahashi, Helio Kiyoshi [UNIFESP]; Straus, Anita Hilda [UNIFESP]; Lindsey, Charles Julian [UNIFESP]; Paiva, Therezinha Bandiera [UNIFESP] (Associação Brasileira de Divulgação Científica, 2009-09-01)
      Multiple cell membrane alterations have been reported to be the cause of various forms of hypertension. The present study focuses on the lipid portion of the membranes, characterizing the microviscosity of membranes ...