Now showing items 1-10 of 96

    • Acute cocaine effects in paradoxical sleep deprived male rats 

      Andersen, Monica Levy [UNIFESP]; Perry, Juliana Cini [UNIFESP]; Tufik, Sergio [UNIFESP] (Elsevier B.V., 2005-02-01)
      Cocaine is a psychomotor drug known to cause behavioural alterations. This study was conducted to characterize behavioural response to acute cocaine injection (7 mg/kg, ip) in paradoxical sleep deprived (PSD) male rats ...

    • Acute total sleep deprivation potentiates cocaine-induced hyperlocomotion in mice 

      Berro, Laís Fernanda [UNIFESP]; Santos, Renan [UNIFESP]; Hollais, André Willian [UNIFESP]; Wuo-Silva, Raphael [UNIFESP]; Fukushiro, Daniela Fukue [UNIFESP]; Mári-Kawamoto, Elisa [UNIFESP]; Costa, Jacqueline Menezes [UNIFESP]; Trombin, Thaís Fernanda [UNIFESP]; Patti, Camila de Lima [UNIFESP]; Grapiglia, Stephanie Berzin [UNIFESP]; Tufik, Sergio [UNIFESP]; Andersen, Monica Levy [UNIFESP]; Frussa Filho, Roberto [UNIFESP] (Elsevier B.V., 2014-09-05)
      Sleep deprivation is common place in modern society. Nowadays, people tend to self-impose less sleep in order to achieve professional or social goals. in the social context, late-night parties are frequently associated ...

    • Aerobic exercise attenuates inhibitory avoidance memory deficit induced by paradoxical sleep deprivation in rats 

      Fernandes, Jansen [UNIFESP]; Zaccaro Baliego, Luiz Guilherme [UNIFESP]; Peixinho-Pena, Luiz Fernando [UNIFESP]; Almeida, Alexandre Aparecido de [UNIFESP]; Venancio, Daniel Paulino [UNIFESP]; Scorza, Fulvio Alexandre [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Arida, Ricardo Mario [UNIFESP] (Elsevier B.V., 2013-09-05)
      The deleterious effects of paradoxical sleep deprivation (SD) on memory processes are well documented. Physical exercise improves many aspects of brain functions and induces neuroprotection. in the present study, we ...

    • Age-related effects on genital reflexes induced by paradoxical sleep deprivation and cocaine in rats 

      Andersen, Monica Levy [UNIFESP]; Bignotto, Magda [UNIFESP]; Papale, Ligia Assumpção [UNIFESP]; Tufik, Sergio [UNIFESP] (Elsevier B.V., 2004-02-01)
      Although sexual function often decreases with age, a recent study demonstrated that paradoxical sleep deprivation (PSD) was effective in inducing penile erection (PE) in 60% of 22-month-old PSD rats after acute cocaine ...

    • Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+) 

      Papale, Ligia A. [UNIFESP]; Makinson, Christopher D.; Ehlen, J. Christopher; Tufik, Sergio [UNIFESP]; Decker, Michael J.; Paul, Ketema N.; Escayg, Andrew (Wiley-Blackwell, 2013-04-01)
      Purpose Mutations in the voltage-gated sodium channel (VGSC) gene SCN1A are responsible for a number of epilepsy disorders, including genetic epilepsy with febrile seizures plus (GEFS+) and Dravet syndrome. in addition to ...

    • AMPA receptors mediate passive avoidance deficits induced by sleep deprivation 

      Dubiela, Francisco Paulino [UNIFESP]; Queiroz, Claudio Marcos; Moreira, Karin Di Monteiro [UNIFESP]; Nobrega, Jose N.; Sita, Luciane Valeria; Tufik, Sergio [UNIFESP]; Hipólide, Débora Cristina [UNIFESP] (Elsevier B.V., 2013-11-15)
      The present study addressed the effects of sleep deprivation (SD) on AMPA receptor (AMPAR) binding in brain regions associated with learning and memory, and investigated whether treatment with drugs acting on AMPAR could ...

    • Anxiety-like effects of meta-chlorophenylpiperazine in paradoxically sleep-deprived mice 

      Polesel, Daniel Ninello; Fukushiro, Daniela Fukue [UNIFESP]; Andersen, Monica Levy [UNIFESP]; Nozoe, Karen Tieme [UNIFESP]; Mari-Kawamoto, Elisa [UNIFESP]; Saito, Luis Paulo [UNIFESP]; Souza Carvalho, Fabio Ramos [UNIFESP]; Alvarenga, Tathiana Aparecida [UNIFESP]; Freitas, Denise [UNIFESP]; Tufik, Sergio [UNIFESP]; Frussa-Filho, Roberto [UNIFESP]; Lanaro, Rafael; Costa, Jose Luiz; Maggi Tavares, Marina Franco (Elsevier B.V., 2014-03-03)
      Chlorophenylpiperazines (CPP) are psychotropic drugs used in nightclub parties and are frequently used in a state of sleep deprivation, a condition which can potentiate the effects of psychoactive drugs. This study aimed ...

    • Are endogenous sex hormones related to DNA damage in paradoxically sleep-deprived female rats? 

      Andersen, Monica Levy [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Alvarenga, Tathiana Aparecida [UNIFESP]; Silva, Andressa [UNIFESP]; Araujo, Paula [UNIFESP]; Zager, Adriano [UNIFESP]; Tenório, Neuli Maria [UNIFESP]; Tufik, Sergio [UNIFESP] (Elsevier B.V., 2010-02-01)
      The aim of this investigation was to evaluate overall DNA damage induced by experimental paradoxical sleep deprivation (PSD) in estrous-cycling and ovariectomized female rats to examine possible hormonal involvement during ...

    • Associação entre o nível de atividade física na vida diária e a função pulmonar em tabagistas adultos 

      Barboza, Miriane Lilian [UNIFESP]; Brisola Barbosa, Alan Carlos [UNIFESP]; Spina, Giovanna Domingues [UNIFESP]; Sperandio, Evandro Fornias [UNIFESP]; Arantes, Rodolfo Leite; de Toledo Gagliard, Antonio Ricardo; Romiti, Marcello; Dourado, Victor Zuniga [UNIFESP] (Soc Brasileira Pneumologia Tisiologia, 2016)
      Objetivo: Determinar se há associações entre o nível de atividade física na vida diária (AFVD) e a função pulmonar em tabagistas adultos. Métodos: Foram selecionados 62 tabagistas adultos de um estudo epidemiológico, ...

    • Association of methamidophos and sleep loss on reproductive toxicity of male mice 

      Maia, Lucas O. [UNIFESP]; Dias Junior, Walter; Carvalho, Loraine S.; Jesus, Luciana R.; Paiva, Greice D.; Araujo, Paula [UNIFESP]; Costa, Marcos F. O.; Andersen, Monica L. [UNIFESP]; Tufik, Sergio [UNIFESP]; Mazaro-Costa, Renata (Elsevier B.V., 2011-09-01)
      This study investigated the effects of organophosphate exposure on the male reproductive system of mice submitted to chronic sleep loss condition. Adult Swiss mice were distributed into 4 groups: control; methamidophos ...