Browsing by Subject "Skeletal muscle"
Now showing items 1-10 of 28
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Calcium influx through L-type channels attenuates skeletal muscle contraction via inhibition of adenylyl cyclases
(Elsevier B.V., 2013-11-15)Skeletal muscle contraction is triggered by acetylcholine induced release of Ca2+ from sarcoplasmic reticulum. Although this signaling pathway is independent of extracellular Ca2+, L-type voltage gated calcium channel ...
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Chronic low frequency/low volume resistance training reduces pro-inflammatory cytokine protein levels and TLR4 mRNA in rat skeletal muscle
(Springer, 2010-08-01)Skeletal muscle is the source of pro- and anti-inflammatory cytokines, and recently, it has been recognized as an important source of interleukin 6 (IL-6), a cytokine that exerts inhibitory effects on several pro-inflammatory ...
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Chronic resistance training decreases MuRF-1 and Atrogin-1 gene expression but does not modify Akt, GSK-3 beta and p70S6K levels in rats
(Springer, 2009-06-01)Long-term adaptation to resistance training is probably due to the cumulative molecular effects of each exercise session. Therefore, we studied in female Wistar rats the molecular effects of a chronic resistance training ...
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Consequências das lesões térmicas extensas no músculo esquelético de crianças: uma revisão sistemática da literatura.
(Universidade Federal de São Paulo, 2021-02-22)As lesões térmicas que ocorrem por derramamento de líquidos quentes estão entre os acidentes mais comuns. Quando superiores a 40% da extensão corporal são consideradas extensas e, além de respostas locais, levam a repercussões ...
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Cyclooxygenase-2 expression in skeletal muscle of knockout mice suffering Duchenne muscular dystrophy
(Springer, 2013-05-01)The purpose of the present study was to investigate the role of cyclooxygenase-2 (COX-2) expression in fibrotic lesion in mdx mice. A total of six male C57BL/10 mice and six C57BL/10-DMD/mdx were distributed into two groups: ...
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Dipeptidyl peptidase IV inhibition upregulates GLUT4 translocation and expression in heart and skeletal muscle of spontaneously hypertensive rats
(Elsevier B.V., 2013-01-05)The purpose of the current study was to test the hypothesis that the dipeptidyl peptidase IV (DPPIV) inhibitor sitagliptin, which exerts anti-hyperglycemic and anti-hypertensive effects, upregulates GLUT4 translocation, ...
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Downhill exercise-induced changes in gene expression related with macrophage polarization and myogenic cells in the triceps long head of rats
(Springer, 2015-02-01)Macrophages are one of the most heterogenic immune cells involved in skeletal muscle regeneration. After skeletal muscle damage, M1 phenotypes exhibit pro-inflammatory reaction. in a later stage, they are converted to M2 ...
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Doxorubicin caused severe hyperglycaemia and insulin resistance, mediated by inhibition in AMPk signalling in skeletal muscle
(Wiley-Blackwell, 2016)Background Cancer is considered the second leading cause of death in the world, and for the treatment of this disease, pharmacological intervention strategies are frequently based on chemotherapy. Doxorubicin (DOX) is one ...
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Efeito do exercício exaustivo sobre aspectos inflamatórios no músculo esquelético e tecido adiposo de ratos
(Universidade Federal de São Paulo (UNIFESP), 2010-04-28)Aim: to verify the inflammatory effects of exhaustive exercise on adipose tissue (mesenteric and retroperitoneal), and skeletal muscle (sóleus: fiber type I, EDL: Fyber type II). Methods: Wistar rats were randomly assigned ...
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Efeito do treinamento físico aeróbio sobre a apoptose da musculatura esquelética de ratos espontaneamente hipertensos
(Universidade Federal de São Paulo (UNIFESP), 2013-02-18)A hipertensão arterial é uma doença que está associada com alterações na musculatura esquelética, podendo existir fenótipos pró-apoptóticos que podem levar às disfunções deste órgão, trazendo sérios riscos e prejuízos à ...
