Browsing by Subject "Sirolimus"
Now showing items 1-9 of 9
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Desenvolvimento de metodologia quantitativa por MALDI-MS para determinação de imunossupressores
(Universidade Federal de São Paulo, 2022-11-25)Os transplantes de órgãos se tornaram um processo rotineiro nos hospitais graças ao avanço dos estudos sobre o corpo humano e das técnicas cirúrgicas, além do desenvolvimento de imunossupressores. Dentre os milhares de ...
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Eficácia, tolerabilidade e segurança do uso do sirolimo após o transplante renal
(Universidade Federal de São Paulo (UNIFESP), 2010-11-24)Objectives: To evaluate the efficacy, safety and tolerability of the administration of sirolimus (SRL) and prednisone in combination with cyclosporine (CSA) or tacrolimus (TAC) after kidney transplantation. Methods: ...
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Exploratory calcineurin inhibitor-free regimens in living-related kidney transplant recipients
(Associação Brasileira de Divulgação Científica, 2007-04-01)Chronic allograft nephropathy is among the major causes of graft loss even in low-risk kidney transplant recipients and correlates with acute nephrotoxic events during the first year post-transplant. Therefore, calcineurin ...
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Impacto dos stents e do sirolimus por via oral na vasomotricidade coronariana dependente e independente do endotélio
(Universidade Federal de São Paulo (UNIFESP), 2012-05-30)Rationale: There is no consensus regarding the impact of stenting on long-term endothelial function. There have been reports of increased endothelial dysfunction with Sirolimus-eluting stents as compared to bare metal ...
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Influência das concentrações sanguíneas de ciclosporina (CSA) e sirolimus(SRL) na incidência e severidade da hiperlipidemia pós-transplante renal
(Universidade Federal de São Paulo (UNIFESP), 2004)Hiperlipidemia e um evento frequente apos o transplante renal e pode se agravar devido ao uso das drogas imunossupressoras. Neste trabalho, nos procuramos identificar a contribuicao das doses e as concentracoes das drogas ...
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Interação farmacocinética do tacrolimo: a influência de prednisona, ácido micofenólico ou sirolimo
(Universidade Federal de São Paulo (UNIFESP), 2010-07-28)Background & objective: This study was conducted to evaluate timedependent pharmacokinetic changes and drug interactions over the first 6 months after transplantation in kidney transplant recipients receiving tacrolimus, ...
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Preservation of graft function in low-risk living kidney transplant recipients treated with a combination of sirolimus and cyclosporine
(Associação Brasileira de Divulgação Científica, 2004-09-01)The use of sirolimus (SRL) in combination with full doses of cyclosporin A (CsA) results in reduced one-year kidney allograft function, which is associated with shorter long-term allograft survival. We determined the effect ...
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Relationship of cyclosporin and sirolimus blood concentrations regarding the incidence and severity of hyperlipidemia after kidney transplantation
(Associação Brasileira de Divulgação Científica, 2006-01-01)The influence of drug concentrations on the development of persistent posttransplant hyperlipidemia was investigated in 82 patients who received cyclosporin A (CsA) and prednisone plus sirolimus (SRL) (52) or azathioprine ...
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Uso de duas concentrações sanguíneas de Sirolimo associado à exposição reduzida de Ciclosporina em receptores de transplante renal de origem étnica negra
(Universidade Federal de São Paulo (UNIFESP), 2009-02-27)Introduction: black recipients have worse long term outcome after kidney transplantation. Immunosuppression regimens with CSA, prednisone and SRL improve kidney transplantation in these patients, lowering the incidence of ...
