Now showing items 1-3 of 3

    • Characterization of thrombin inhibitory mechanism of rAaTI, a Kazal-type inhibitor from Aedes aegypti with anticoagulant activity 

      Watanabe, Renata Midori Okuta [UNIFESP]; Tanaka-Azevedo, Anita M.; Araujo, Mariana da Silva [UNIFESP]; Juliano, Maria Aparecida [UNIFESP]; Tanaka, Aparecida Sadae [UNIFESP] (Elsevier B.V., 2011-03-01)
      Saliva of blood-sucking arthropods contains a complex mixture of anti-haemostatic, anti-inflammatory and immune-modulator compounds. Among anti-haemostatic factors, there are anticoagulants, vasodilators and platelet ...

    • A novel trypsin Kazal-type inhibitor from Aedes aegypti with thrombin coagulant inhibitory activity 

      Watanabe, Renata M. O. [UNIFESP]; Soares, Tatiane S. [UNIFESP]; Morais-Zani, Karen; Tanaka-Azevedo, Anita M.; Maciel, Ceres; Capurro, Margareth L.; Torquato, Ricardo J. S. [UNIFESP]; Tanaka, Aparecida S. [UNIFESP] (Elsevier B.V., 2010-08-01)
      Kazal-type inhibitors play several important roles in invertebrates, such as anticoagulant, vasodilator and antimicrobial activities. Putative Kazal-type inhibitors were described in several insect transcriptomes. in this ...

    • Role of the medial septal area on pilocarpine-induced salivary secretion and water intake 

      Paulin, Renata Fabris; Menani, Jose V.; Colombari, Eduardo [UNIFESP]; De Paula, Patricia Maria; Almeida Colombari, Debora Simoes (Elsevier B.V., 2009-10-28)
      Peripheral injection of pilocarpine, a cholinergic muscarinic agonist, induces salivation, water intake and hypertension. the medial septal area (MSA) is involved in cardiovascular control and fluid-electrolyte balance. ...