Browsing by Subject "SNPs"
Now showing items 1-7 of 7
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Associação do fator de crescimento vásculo-endotelial e de polimorfismos do seu gene com a gravidez ectópica
(Universidade Federal de São Paulo (UNIFESP), 2010-03-31)Objetivo: Analise do fator de crescimento vasculo-endotelial (VEGF) como marcador sorologico no diagnostico da gravidez ectopica. Outrossim, e desiderato deste projeto avaliar se as variantes polimorficas -460 T/C (rs833061), ...
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Association study of SNPs of genes IFNGR1 (rs137854905), GSTT1 (rs71748309), and GSTP1 (rs1695) in gastric cancer development in samples of patient in the northern and northeastern Brazil
(Springer, 2014-05-01)Cancer is a multifactorial disease with a high mortality rate in Brazil and worldwide. Gastric cancer (GC) is considered the fourth type of malignancy more frequent in the population worldwide and the second leading cause ...
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Avaliação do uso de Hadoop e MapReduce para aumento de eficiência no gerenciamento de dados biológicos
(Universidade Federal de São Paulo, 2019-12-11)"Os avanços tecnológicos da era digital vem contribuindo para o crescimento exponencial do volume de dados gerado pelo estilo de vida moderno, tornando relevante o estudo de Big Data e seus métodos e técnicas. A Bioinformática ...
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Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of virulence and resistance mechanisms
(Biomed Central Ltd, 2014-01-22)Background: Klebsiella pneumoniae is an important opportunistic pathogen associated with nosocomial and community-acquired infections. A wide repertoire of virulence and antimicrobial resistance genes is present in K. ...
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Molecular studies reveal that A134T, G156A and G1333A SNPs in the CD177 gene are associated with atypical expression of human neutrophil antigen-2
(Wiley-Blackwell, 2010-02-01)Background and ObjectivesThe human neutrophil antigen-2 (HNA-2) is expressed on a subpopulation of neutrophils as most subjects present a negative plus a positive HNA-2 population of neutrophils. the number of neutrophils ...
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A phased SNP-based classification of sickle cell anemia HBB haplotypes
(Biomed Central Ltd, 2017)Background: Sickle cell anemia causes severe complications and premature death. Five common beta-globin gene cluster haplotypes are each associated with characteristic fetal hemoglobin (HbF) levels. As HbF is the major ...
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Polimorfismos no genoma mitocondrial associados à Esclerose Lateral Amiotrófica
(Universidade Federal de São Paulo (UNIFESP), 2019-03-28)Mitochondria play central roles in cell maintenance that goes beyond energy production, such as regulation of intracellular Calcium and apoptosis. Although mitochondrial alterations have been associated with Amyotrophic ...
