Browsing by Subject "Resistência"

Algoritmo para Predição de Seleção de Resistência Aos Inibidores de Ns5a do Vírus da Hepatite C

Almeida, Douglas De Andrade De [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2020-12-14)

Summary Objective: To develop an algorithm that, based on the genetic sequence of the HCV infecting virus, can estimate which are the best therapeutic treatments with the least probability of resistance selection for NS5A ...

Análise de prevalência do perfil mutacional de resistência aos antirretrovirais entre indivíduos em falha ao primeiro esquema antirretroviral com ITRNN no Brasil

Dias, Danilo Araujo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2020-03-05)

Introduction: Antiretroviral treatment has proven to be increasingly effective and well-tolerated over time. However, drug resistance mutations have an important impact and could be a major issue especially to cases in ...

Avaliação da prevalência de Carbapenemases em amostras de Enterobactérias isoladas no complexo Hospital São Paulo/UNIFESP

Nicoletti, Adriana Giannini [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-04-28)

Objective: The aim of this study was to evaluate the presence of carbapenemases in Enterobacteriaceae isolated in Hospital São Paulo Complex (UNIFESP) between June and July 2008. Methods: The presence of MBL- and KPC-encoding ...

Avaliação Por Ngs As Mutações De Resistência Nos Genes Da Integrase, Protease E Transcriptase Reversa Do Hiv-1 Em Indivíduos Em Falha Virológica

Duro, Rodrigo Lopes Sanz [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2017-03-15)

Introduction: With the introduction of Antiretroviral Therapy, there was an improvement in the quality of life in individuals with Human Immunodeficiency Virus. However, the selective pressure exerted by these drugs had a ...

Baixa prevalência de não resposta virológica no resgate antirretroviral e fatores associados em uma coorte de pacientes vivendo com HIV-1 com falha virológica e resistência a múltiplos antirretrovirais

Sachetti, Rachel Juliana [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-12-18)

Introduction: The treatment of patients with antiretroviral resistance, involving the association of potent drugs with high genetic barrier is very effective. However, rescue therapies have been poorly studied in routine ...

Caracterização microbiológica de Klebsiella pneumoniae produtora de enzima KPC isoladas em pacientes de um hospital de alta complexidade durante o período de cinco anos (2009 – 2014)

Fonseca, Juliane De Mello [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018)

Background: Health care-related infections (HAIs) represent a challenge for global public health and when associated with resistance to antimicrobials, they can negatively impact the increase in hospital stay, health – ...

Estudo do papel dos receptores Two-Pore Channels na quimiossensibilização ao Sorafenibe em linhagem celular de hepatocarcinoma humano

Lins, Isis Valeska Freire [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2020-03-26)

Sorafenib is a tyrosine kinase inhibitor approved as a first-line palliative treatment for hepatocellular carcinoma (HCC). Despite being well tolerated in the clinic, some patients present resistance to the treatment. Thus, ...