Browsing by Subject "Reserpine"
Now showing items 1-10 of 12
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Attenuation of motor deficits by hydroethanolic extract of Poincianella pyramidalis in a Parkinson's disease model
(Univ Santiago Chile Casa, 2017)The present study aimed to evaluate the possible neuroprotective effect of the hydroethanolic extract of Poincianella pyramidalis (EFIPp) (Tul.) L. P. Queiroz (Fabaceae), an endemic plant found in Northeastern Brazil, ...
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Beneficial effects of vitamin C and vitamin E on reserpine-induced oral dyskinesia in rats: Critical role of striatal catalase activity
(Elsevier B.V., 2005-06-01)Oral dyskinesias are implicated in a series of neuropathologies and have been associated to an increase in oxidative stress. Several antioxidants, including vitamin E, decrease reserpine-induced oral clyskinesia (OD) in ...
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Cognitive, motor and tyrosine hydroxylase temporal impairment in a model of parkinsonism induced by reserpine
(Elsevier B.V., 2013-09-15)Studies have suggested that cognitive deficits can precede motor alterations in Parkinson's disease (PD). However, in general, classic animal models are based on severe motor impairment after one single administration of ...
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Diferenças sexuais no desenvolvimento de Parkinsonismo induzido pelo tratamento repetido com Reserpina
(Universidade Federal de São Paulo (UNIFESP), 2019-09-26)Parkinson’s disease (PD) is the second most common age-related neurodegenerative disease. Studies show that PD is more frequent in men than women. The main symptoms of the disease are motor signs such as resting tremor, ...
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Efeitos da administração crônica do extrato de casca de uva em camundongos submetidos a um modelo progressivo da Doença de Parkinson
(Universidade Federal de São Paulo (UNIFESP), 2020-07-21)Parkinson's disease (PD) is a neurodegenerative disease affecting mainly the elderly population. PD etiology remains unknown, however, evidence shows that genetic predisposition and environmental factors, such as contamination ...
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Efeitos da privação de sono sobre camundongos submetidos a um modelo farmacológico da Doença de Parkinson
(Universidade Federal de São Paulo (UNIFESP), 2020-03-26)Parkinson's disease (PD) is a degenerative, chronic and progressive disease, characterized primarily by motor dysfunctions. However, patients may also exhibit non-motor symptoms, which include sleep disorders, anxiety, ...
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Exposure to an enriched environment facilitates motor recovery and prevents short-term memory impairment and reduction of striatal BDNF in a progressive pharmacological model of parkinsonism in mice
(Elsevier Science Bv, 2017)Previous studies showed that the repeated administration with a low dose of reserpine (RES) induces a gradual appearance of motor signs and cognitive deficits compatible with parkinsonism in rodents. Environmental stimulation ...
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Important role of striatal catalase in aging- and reserpine-induced oral dyskinesia
(Elsevier B.V., 2004-08-01)Tardive dyskinesia, the most serious iatrogenic movement disorder, has been tentatively associated with nigrostriatal dopaminergic supersensitivity and with oxidative stress. It is also suggested that long-term neuroleptic ...
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Investigação da relação entre predisposição ao comportamento tipo depressivo e as alterações motoras e não-motoras no modelo de parkinsonismo progressivo induzido por reserpina em camundongos
(Universidade Federal de São Paulo (UNIFESP), 2020-07-30)Parkinson's disease (PD) is a degenerative, chronic and progressive disease, which mainly affects elderly people. Its main features are the so-called motor symptoms, which include tremors at rest, impaired voluntary movement, ...
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Perfil inflamatório do sistema nervoso de ratos submetidos a um modelo farmacológico de Doença de Parkinson
(Universidade Federal de São Paulo (UNIFESP), 2020-10-29)Objective: The aim of this study was to investigate whether the model of Parkinson's Disease (PD) induced by low doses of reserpine leads to neuroinflammation, which is a clinical characteristic of PD. Methods: 6-month-old ...
