Browsing by Subject "Reactive oxygen species"
Now showing items 1-10 of 14
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1,4-Diamino-2-butanone, a wide-spectrum microbicide, yields reactive species by metal-catalyzed oxidation
(Elsevier B.V., 2011-06-15)The alpha-aminoketone 1,4-diamino-2-butanone (DAB), a putrescine analogue, is highly toxic to various microorganisms, including Trypanosoma cruzi. However, little is known about the molecular mechanisms underlying DAB's ...
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Anatomical specificity of the brain in the modulation of Neuroglobin and Cytoglobin genes after chronic bisphenol a exposure
(Springer/Plenum Publishers, 2017)The aim of this study was to investigate the influence of Bisphenol A (BPA) exposure on Neuroglobin (Ngb) and Cytoglobin (Cygb) as well as oxidative stress gene expression in the cerebellum, hippocampus, hypothalamus and ...
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Direct renin inhibition is not enough to prevent reactive oxygen species generation and vascular dysfunction in renovascular hypertension
(Elsevier Science Bv, 2018)Renin-angiotensin system activation promotes oxidative stress and endothelial dysfunction. However, no previous study has examined the effects of the renin inhibitor aliskiren, either alone or combined with angiotensin II ...
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Efeito do treinamento físico aeróbico sobre os níveis de espécies reativas de oxigênio na aorta de ratas ovariectomizadas
(Universidade Federal de São Paulo (UNIFESP), 2013-12-17)Sabe-se que a hipertensão arterial é uma doença multifatorial que atinge grande parte da população adulta, principalmente mulheres em idade mais avançada no período da pós-menopausa. Isso se deve a alterações relacionadas ...
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Efeitos da ingestão de chocolate 70% cacau sobre o sistema imunológico e estresse oxidativo após exercício físico extenuante
(Universidade Federal de São Paulo (UNIFESP), 2014-02-26)It is known that physical exercise can stimulate or depress the immune system. This immunomodulatory role depends on several factors including the intensity, duration of exercise as well as fitness level and nutritional ...
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Effect of different semen extenders for the storage of chilled sperm in Tigrina (Leopardus tigrinus)
(Elsevier Science Inc, 2017)To enhance the conservation of endangered populations, the present study aimed to evaluate whether Tigrinas (Leopardus tigrinus) sperm could be conserved under refrigeration for short periods while maintaining sufficient ...
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Lipopolysaccharide-induced expression of cell surface receptors and cell activation of neutrophils and monocytes in whole human blood
(Associação Brasileira de Divulgação Científica, 2010-09-01)Lipopolysaccharide (LPS) activates neutrophils and monocytes, inducing a wide array of biological activities. LPS rough (R) and smooth (S) forms signal through Toll-like receptor 4 (TLR4), but differ in their requirement ...
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Nandrolone combined with strenuous resistance training reduces vascular nitric oxide bioavailability and impairs endothelium-dependent vasodilation
(Elsevier Science Inc, 2018)Anabolic Androgenic Steroids (AASs) misuse has increased among adolescents and recreational athletes due to their potential effects on muscle hypertrophy. On the other hand, AAS might induce alterations on cardiovascular ...
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A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production
(Springer, 2013-06-01)In cancer-treatment, potentially therapeutic drugs trigger their effects through apoptotic mechanisms. Generally, cell response is manifested by Bcl-2 family protein regulation, the impairment of mitochondrial functions, ...
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O papel da espécies reativas de oxigênio e do antioxidante astaxantina em oócitos bovinos submetidos ao estresse térmico in vitro
(Universidade Federal de São Paulo, 2013-08-21)Condições ambientais adversas, tais como temperatura e umidade elevada, limitam a exploração do máximo potencial genético animal. Em bovinos, o estresse térmico materno compromete a fertilidade de vacas leiteiras, resultando ...
