Browsing by Subject "Rat"

Now showing items 1-10 of 92

    • Acute crack cocaine exposure induces genetic damage in multiple organs of rats 

      Moretti, Eduardo Gregolin [UNIFESP]; Yujra, Veronica Quispe [UNIFESP]; Claudio, Samuel Rangel [UNIFESP]; Silva, Marcelo Jose Dias; Vilegas, Wagner; Pereira, Camilo Dias Seabra [UNIFESP]; De Oliveira, Flavia [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP] (Springer Heidelberg, 2016)
      Crack cocaine is a very toxic product derived from cocaine. The aim of this study was to evaluate genetic damage in multiple organs of rats following acute exposure to crack cocaine. A total of 20 Wistar rats were distributed ...

    • Acute Spinal Cord Injury Induces Genetic Damage in Multiple Organs of Rats 

      Medalha, Carla Christina [UNIFESP]; Polesel, Fernanda Sato [UNIFESP]; Silva, Victor Hugo Pereira da [UNIFESP]; Martins, Renato Almeida [UNIFESP]; Pozzi, Renan [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP] (Springer, 2012-08-01)
      Spinal cord injury (SCI) is a devastating condition with important functional and psychological consequences. However, the underlying mechanisms by which these alterations occur are still not fully understood. the aim of ...

    • Administration of lopinavir/ritonavir association during rat pregnancy: maternal and fetal effects 

      Kulay Júnior, Luiz [UNIFESP]; Hagemann, Cristiane Cadore de Farias [UNIFESP]; Nakamura, Mary Uchiyama [UNIFESP]; Simoes, Ricardo Santos [UNIFESP]; Carvalho, Adelino Moreira de [UNIFESP]; Oliveira-Filho, Ricardo Martins [UNIFESP]; Espiridião, Silvia [UNIFESP] (I R O G Canada, Inc, 2013-01-01)
      Purpose: To evaluate the effects of the association of lopinavir and ritonavir administered during the whole period of rat pregnancy. Methods: 62 Wistar rats of the EPM-1 variant weighing about 200 g were randomly divided ...

    • Alteration of purinergic P2X(4) and P2X(7) receptor expression in rats with temporal-lobe epilepsy induced by pilocarpine 

      Doná, Flávia [UNIFESP]; Ulrich, Henning; Persike, Daniele Suzete [UNIFESP]; Conceição, Isaltino Marcelo da [UNIFESP]; Blini, João Paulo [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP]; Silva Fernandes, Maria Jose [UNIFESP] (Elsevier B.V., 2009-02-01)
      Although ATP and P2X receptor activity have been lately associated with epilepsy, little is known regarding their exact roles in epileptogenesis. Temporal-lobe epilepsy (TLE) in rat was induced by pilocarpine in order to ...

    • Analysis of the ki-67 index in the vaginal epithelium of castrated rats treated with tamoxifen 

      Nery-Aguiar, Afif Rieth; Aguiar, Yousef Qathaf; Conde Junior, Airton Mendes; Alencar, Airlane Pereira; Tavares, Cleciton Braga; Lopes-Costa, Pedro Vitor; Nazario, Afonso Celso [UNIFESP]; da Silva, Benedito Borges (Hospital clinicas, univ sao paulo, 2016)
      OBJECTIVES: Vaginal atrophy and breast cancer are common conditions in postmenopausal women and tamoxifen is the standard endocrine treatment for hormone-sensitive tumors. The present study aimed to assess the effect of ...

    • Androgen deprivation from pre-puberty to peripuberty interferes in proteins expression in pubertal and adult rat epididymis 

      Perobelli, Juliana Elaine; Patrão, Marilia Tavares Coutinho da Costa [UNIFESP]; Fernandez, Carla Dal Bianco; Sanabria, Marciana; Klinefelter, Gary R.; Avellar, Maria Christina Werneck [UNIFESP]; Kempinas, Wilma De Grava (Elsevier B.V., 2013-07-01)
      Few studies have focused on experimental testosterone deprivation in immature animals. Therefore, this study used sexually immature rats aiming to evaluate the testes and epididymis histology and proteins expression in ...

    • Antimutagenic and antigenotoxic potential of grape juice concentrate in blood and liver of rats exposed to cadmium 

      Moura, Carolina Foot Gomes de [UNIFESP]; Ribeiro, Flavia Andressa Pidone [UNIFESP]; Jesus, Gustavo Protasio Pacheco de [UNIFESP]; Silva, Victor Hugo Pereira da [UNIFESP]; Oshima, Celina Tizuko Fujiyama [UNIFESP]; Gollucke, Andrea Pittelli Boiago [UNIFESP]; Aguiar, Odair [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP] (Springer, 2014-11-01)
      The aim of this study was to evaluate the antimutagenic and antigenotoxic potential of grape juice concentrate in rodent organs exposed to cadmium chloride intoxication. A total of 15 Wistar rats were distributed into three ...

    • Avaliação de genotoxicidade em múltiplos órgãos após compressão dos membros inferiores de ratos 

      Carneiro Neto, Nicola Jorge [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014-10-14)
      Muscle injury is a common trauma in modern society as a result of mass disasters, muscle penetration by high velocity projectiles, blunt external trauma, or by prolonged immobilization in comatose patients after head trauma, ...

    • Avaliação do potencial nutracêutico de extrato de cenoura roxa (daucus carota lSspSativus varAtrorubens alef) em múltiplos tecidos (sangue periférico, medula óssea e fígado) de ratos expostos ao cloreto de cádmio 

      Claudio, Saumel Rangel [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-03-31)
      The aim of this study was to investigate if purple carrot extract is able to protect against the noxious activities induced by cadmium exposure in multiple organs of rats. For this purpose, histopathological analysis, ...

    • Bronchial tree Architecture in Mammals of Diverse Body Mass 

      Monteiro, Adilson [UNIFESP]; Smith, Ricardo Luiz [UNIFESP] (Soc Chilena Anatomia, 2014-03-01)
      The anatomy of mammal's lung air space constitutes the bronchial tree which disposition is associated to air flux dynamics. Casts obtained from human, pig and rat lungs were studied to analyze possible differences of the ...