Browsing by Subject "Proteasome inhibitor"

Now showing items 1-3 of 3

    • Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell 

      Morais, Katia Luciano Pereira [UNIFESP]; Fernandes Pacheco, Mario Thiego; Berra, Carolina Maria; Bosch, Rosemary V.; Sciani, Juliana Mozer; Chammas, Roger [UNIFESP]; Saito, Renata de Freitas; Iqbal, Asif; Chudzinski-Tavassi, Ana Marisa [UNIFESP] (Springer, 2016)
      During the last two decades, new insights into proteasome function and its role in several human diseases made it a potential therapeutic target. In this context, Amblyomin-X is a Kunitz-type FXa inhibitor similar to ...

    • Tick salivary gland as potential natural source for the discovery of promising antitumor drug candidates 

      Chudzinski-Tavassi, Ana Marisa; Morais, Katia L. P. [UNIFESP]; Pacheco, Mario Thiego Fernandes; Pasqualoto, Kerly Fernanda Mesquita; de Souza, Jean Gabriel [UNIFESP] (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)
      Nowadays, the relationship between cancer blood coagulation is well established. Regarding biodiversity and bioprospection, the tick biology has become quite attractive natural source for coagulation inhibitors, since its ...

    • Tick salivary gland as potential natural source for the discovery of promising antitumor drug candidates 

      Chudzinski-Tavassi, Ana Marisa; Morais, Katia L. P. [UNIFESP]; Pacheco, Mario Thiego Fernandes; Pasqualoto, Kerly Fernanda Mesquita; de Souza, Jean Gabriel [UNIFESP] (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)
      Nowadays, the relationship between cancer blood coagulation is well established. Regarding biodiversity and bioprospection, the tick biology has become quite attractive natural source for coagulation inhibitors, since its ...