Browsing by Subject "Primary immunodeficiency"

Now showing items 1-9 of 9

    • Advancing the management of primary immunodeficiency diseases in Latin America: Latin American Society for Immunodeficiencies (LASID) Initiatives 

      Condino-Neto, A.; Franco, J. L.; Espinosa-Rosales, F. J.; Leiva, L. E.; King, A.; Porras, O.; Oleastro, M.; Bezrodnik, L.; Grumach, A. S.; Costa-Carvalho, B. T. [UNIFESP]; Sorensen, R. U. (Elsevier B.V., 2012-05-01)
      Primary immunodeficiency diseases (PIDD) are associated with significant morbidity and mortality and result in a significant public health burden. This is in part due to the lack of appropriate diagnosis and treatment of ...

    • BCG vaccination in patients with severe combined immunodeficiency: Complications, risks, and vaccination policies 

      Marciano, Beatriz E.; Huang, Chiung-Yu; Joshi, Gyan; Rezaei, Nima; Costa-Carvalho, Beatriz Tavares [UNIFESP]; Allwood, Zoe; Ikinciogullari, Aydan; Reda, Shereen M.; Gennery, Andrew; Thon, Vojtech; Espinosa-Rosales, Francisco; Al-Herz, Waleed; Porras, Oscar; Shcherbina, Anna; Szaflarska, Anna; Kilic, Sebnem; Franco, Jose L.; Gomez Raccio, Andrea C.; Roxo, Persio; Esteves, Isabel; Galal, Nermeen; Grumach, Anete Sevciovic; Al-Tamemi, Salem; Yildiran, Alisan; Orellana, Julio C.; Yamada, Masafumi; Morio, Tomohiro; Liberatore, Diana; Ohtsuka, Yoshitoshi; Lau, Yu-Lung; Nishikomori, Ryuta; Torres-Lozano, Carlos; Mazzucchelli, Juliana T. L. [UNIFESP]; Vilela, Maria M. S. [UNIFESP]; Tavares, Fabiola S. [UNIFESP]; Cunha, Luciana; Pinto, Jorge A.; Espinosa-Padilla, Sara E.; Hernandez-Nieto, Leticia; Elfeky, Reem A.; Ariga, Tadashi; Toshio, Heike; Dogu, Figen; Cipe, Funda; Formankova, Renata; Enriqueta Nunez-Nunez, M.; Bezrodnik, Liliana; Marques, Jose Goncalo; Pereira, Maria I.; Listello, Viviana; Slatter, Mary A.; Nademi, Zohreh; Kowalczyk, Danuta; Fleisher, Thomas A.; Davies, Graham; Neven, Benedicte; Rosenzweig, Sergio D. (Elsevier B.V., 2014-04-01)
      Background: Severe combined immunodeficiency (SCID) is a syndrome characterized by profound T-cell deficiency. BCG vaccine is contraindicated in patients with SCID. Because most countries encourage BCG vaccination at birth, ...

    • Fetal-onset IPEX: Report of two families and review of literature 

      Xavier-da-Silva, Mariana Moraes; Moreira-Filho, Carlos A.; Suzuki, Edson; Patricio, Francy [UNIFESP]; Coutinho, Antonio; Carneiro-Sampaio, Magda (Elsevier B.V., 2015-02-01)
      Early-life autoimmunity is an IPEX characteristic, however intrauterine forms had not yet been described. Here, two unrelated families with clear evidence of fetal-onset IPEX are reported. One had 5 miscarriages of males ...

    • Guidelines for the use of human immunoglobulin therapy in patients with primary immunodeficiencies in Latin America 

      Condino-Neto, A.; Costa-Carvalho, B. T. [UNIFESP]; Grumach, A. S.; King, A.; Bezrodnik, L.; Oteastro, M.; Leiva, L.; Porras, O.; Espinosa-Rosales, F. J.; Franco, J. L.; Sorensen, R. U. (Elsevier B.V., 2014-05-01)
      Antibodies are an essential component of the adaptative immune response and hold long-term memory of the immunological experiences throughout life. Antibody defects represent approximately half of the well-known primary ...

    • Immediate infusion-related adverse reactions to intravenous immunoglobulin in a prospective cohort of 1765 infusions 

      Bichuetti-Silva, Danielli C. [UNIFESP]; Furlan, Fernanda P. [UNIFESP]; Nobre, Fernanda A. [UNIFESP]; Pereira, Camila T. M. [UNIFESP]; Goncalves, Tessa R. T. [UNIFESP]; Gouveia-Pereira, Mariana [UNIFESP]; Rota, Rafael [UNIFESP]; Tavares, Lusinete [UNIFESP]; Mazzucchelli, Juliana T. L. [UNIFESP]; Costa-Carvalho, Beatriz T. [UNIFESP] (Elsevier B.V., 2014-12-01)
      Intravenous immunoglobulin (WIG) is increasingly recommended for many diseases apart from primary immunodeficiency diseases (PID). Although effective and safe, adverse reactions may occur. We conducted a 2-year prospective ...

    • Latin American challenges with the diagnosis and treatment of primary immunodeficiency diseases 

      Costa-Carvalho, Beatriz [UNIFESP]; Gonzalez-Serrano, Maria; Espinosa-Padilla, Sara; Segundo, Gesmar (Taylor & Francis Ltd, 2017)
      Introduction: diagnosis of primary immunodeficiency diseases (PID) is still a challenge in many countries in Latin America (LA), especially those that face social and economic problems. The creation of a society was ...

    • Neonatal screening for severe combined immunodeficiency in Brazil 

      Patto Kanegae, Marilia Pyles; Barreiros, Lucila Akune; Lessa Mazzucchelli, Juliana Themudo [UNIFESP]; Hadachi, Sonia Marchezi; de Figueiredo Ferreira Guilhoto, Laura Maria; Acquesta, Ana Lucia; Genov, Isabel Rugue [UNIFESP]; Holanda, Silvia Maia; Watanabe Di Gesu, Regina Sumiko; Goulart, Ana Lucia [UNIFESP]; Nunes dos Santos, Amelia Miyashiro [UNIFESP]; Bellesi, Newton; Costa-Carvalho, Beatriz Tavares [UNIFESP]; Condino-Neto, Antonio (Soc Brasil Pediatria, 2016)
      Objective: To apply, in Brazil, the T-cell receptor excision circles (TRECs) quantification technique using real-time polymerase chain reaction in newborn screening for severe combined immunodeficiency and assess the ...

    • Severe Combined Immunodeficiency in Brazil: Management, Prognosis, and BCG-Associated Complications 

      Mazzucchelli, J. T. L. [UNIFESP]; Bonfim, C.; Castro, G. G.; Condino-Neto, A. A.; Costa, N. M. X.; Cunha, L.; Dantas, E. O.; Dantas, V. M.; Moraes-Pinto, M. I. de [UNIFESP]; Fernandes, J. F.; Goes, H. C.; Goudouris, E.; Grumach, A. S.; Guirau, L. M. B.; Kuntze, G.; Mallozzi, M. C.; Monteiro, F. P.; Moraes, L. S. L.; Nudelman, V.; Pinto, J. A.; Rizzo, M. C. V.; Porto-Neto, A. C.; Roxo-Junior, P.; Ruiz, M.; Rullo, V. E. V.; Seber, A. [UNIFESP]; Takano, O. A.; Tavares, F. S.; Toledo, E.; Vilela, M. M. S.; Costa-Carvalho, B. T. [UNIFESP] (Esmon Publicidad S A, 2014-01-01)
      Background: Severe combined immunodeficiency (SCID) is one of the most severe forms of primary immunodeficiency. The objectives of this study were to analyze the diagnosis, treatment, and prognosis of SCID in Brazil and ...

    • The use of reverse transcription-PCR for the diagnosis of X-linked chronic granulomatous disease 

      Agudelo-Flórez, Piedad; López, Juan Alvaro; Redher, Jussara; Carneiro-Sampaio, Magda Maria Sales; Costa-Carvalho, Beatriz Tavares [UNIFESP]; Grumach, Anete Sevciovic; Condino-Neto, Antonio (Associação Brasileira de Divulgação Científica, 2004-05-01)
      Chronic granulomatous disease (CGD) is an inherited disorder of the innate immune system characterized by a defective oxidative burst of phagocytes and subsequent impairment of their microbicidal activity. Mutations in one ...